Results 211 to 220 of about 3,259,279 (281)

Unbiased inference for echocardiogram urgency prediction using double machine learning. [PDF]

PLoS One
Jiang Y, Zhang W, Huang YL, MacKenzie C, Li Q.   +4 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Ensemble machine learning-based sensitivity and parametric assessment of headed stud shear connectors behavior in composite construction. [PDF]

Sci Rep
Habib A, Alhashash M, Al Houri A, Habib M, Junaid MT, Altoubat S, Maalej M.   +6 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Analysing the impact of complex multimorbidity on health-related quality of life. [PDF]

Qual Life Res
Walsh S, Gillespie P, Hobbins A, O'Neill C, McCarthy C, Moriarty F, Clyne B, Boland F, Smith SM, on behalf the SPPiRE Study Research Team.   +9 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Micellar extraction followed by flow injection ICP-AES for preconcentration and determination of aluminium ions. [PDF]

RSC Adv
Shariati S, Yamini Y, Faraji M, Saleh A, Bozorgzadeh E.   +4 more
europepmc   +1 more source

CR manifolds in Grauert tubes (Workshop for young mathematicians on Several Complex Variables)

, 2003
Eisuke Koizumi
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source