Results 101 to 110 of about 4,841,505 (283)

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

The SARS-coronavirus-host interactome [PDF]

, 2011
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to ...
Brunn, Albrecht von, Steffen, Imke, Kögl, Manfred, Schwegmann-Wessels, Christel, Pumpor, Ksenia, Müller, Marcel A., Herzog, Petra, Kuri, Thomas, Ditt, Vanessa, Weber, Friedemann, Schwarz, Frank, Pfefferle, Susanne, Schöpf, Julia, Kallies, Stefan, Herrler, Georg, Carbajo-Lozoya, Javier, Zimmer, Ralf, Hilgenfeld, Rolf, Friedel, Caroline C., Dall'Armi, Ekatarina von, Drosten, Christian, Niemeyer, Daniela, Thiel, Volker, Züst, Roland, Stellberger, Thorsten, Thiel, Heinz-Jürgen, Pöhlmann, Stefan, Haas, Juergen G.   +27 more
core   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Modelling the utility of body temperature readings from primary care consults for SARS surveillance in an army medical centre. [PDF]

, 2006
INTRODUCTION: There is interest in surveillance systems for outbreak detection at stages where clinical presentation would still be undifferentiated. Such systems focus on detecting clusters of syndromes in excess of baseline levels, which may indicate ...
Tan, Iain BH, Ng, Yih-Yng, Chen, Mark IC
core   +1 more source

Middle East Respiratory Syndrome Coronavirus (MERS-CoV): State of the Science

Microorganisms, 2020
Coronaviruses belong to a large family of viruses that can cause disease outbreaks ranging from the common cold to acute respiratory syndrome. Since 2003, three zoonotic members of this family evolved to cross species barriers infecting humans and ...
Ahmed Mostafa, Ahmed Kandeil, Mahmoud Shehata, Rabeh El Shesheny, Abdallah M. Samy, Ghazi Kayali, Mohamed A. Ali   +6 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

SARS-CoV antibody prevalence in all Hong Kong patient contacts. [PDF]

, 2004
A total of 1,068 asymptomatic close contacts of patients with severe acute respiratory (SARS) from the 2003 epidemic in Hong Kong were serologically tested, and 2 (0.19%) were positive for SARS coronavirus immunoglobulin G antibody. SARS rarely manifests
Law, Y-L, Thomas Tsang, Leung, Pak-Yin, Chau, P, Ghani, Azra C, Law, YL, Pak-Yin Leung, Ghani, AC, Lam, TH, Alex Fu, Lam, Tai-Hing, Chan, SKK, Fraser, C, Ng, T, Peiris, JS Malik, Law, Yuk-lung, Donnelly, CA, Ng, Tonny, Fu, Alex, Hedley, AJ, Patsy Chau, Chung, PH, Pui-Hong Chung, Christl A. Donnelly, Anderson, Roy M, Steve K.K. Chan, Chung, Pui-Hong, Riley, Steven, Hedley, Anthony J, Anthony J. Hedley, Chan, Steve KK, Lam, T-H, J.S. Malik Peiris, Tsang, T, Tsang, Thomas, Wilina Lim, Tina Mok, Leung, Gabriel M, Tonny Ng, Christophe Fraser, Anderson, RM, Lim, Wilina, Chau, Patsy, Azra C. Ghani, Mok, Tina, Lim, W, Leung, GM, Ferguson, Neil M, Fraser, Christophe, Mok, T, Leung, PY, Yuk-lung Law, Ferguson, NM, Roy M. Anderson, Fu, A, Tai-Hing Lam, Leung, P-Y, Donnelly, Christi A, Chung, P-H, Steven Riley, Riley, S, Peiris, JSM, Neil M. Ferguson, Gabriel M. Leung   +63 more
core   +1 more source

Severe Acute Respiratory Syndrome : An Update

Medical Journal Armed Forces India, 2007
The medical community will long remember the winter of 2002. An outbreak of an unusual form of respiratory illness started in the Southern Chinese province of Guangdong. It was characterised by a severe form of pneumonia caused by typical or atypical organisms. It also had a propensity to spread among household contacts and healthcare providers [1]. It
Mehta, SR, Sashindran, VK, Kumar, K, Gupta, A   +3 more
openaire   +2 more sources

Deep Eutectic Solvent‐Enhanced PEDOT: PSS/NR Foam Piezoresistive Sensor for High‐Sensitivity Wearable Devices and Sleep Monitoring Applications

Advanced Materials Interfaces, EarlyView.
A high‐performance piezoresistive foam sensor is developed by integrating natural rubber, PEDOT: PSS, and a deep eutectic solvent (DES). DES effectively detaches insulating PSS from PEDOT, dramatically amplifying electrical conductivity and sensitivity.
Shun Zhang, Jizu Ma, Peng Yu, Lei Tan, Yan Xu   +4 more
wiley   +1 more source

Human monoclonal antibody combination against SARS coronavirus : synergy and coverage of escape mutants [PDF]

, 2006
Background: Experimental animal data show that protection against severe acute respiratory syndrome coronavirus (SARS-CoV) infection with human monoclonal antibodies (mAbs) is feasible.
Peiris, Joseph S. M., Cox Freek, Doerr, Hans Wilhelm, Brink, Edward van den, van den Brink Edward N, Hans Wilhelm Doerr, ter Meulen Jan, Doerr Hans Wilhelm, Cheung, Chung Y., de Kruif John, van Deventer, Els, Jaap Goudsmit, Leo L. M., Poon, Leo L M Poon, Marissen Wilfred E, Marissen, Wilfred E., Poon Leo L. M, van den Brink, Edward N., Chow Vincent T, Chung Y Cheung, Wolfgang Preiser, Leung, Cynthia S.W., Preiser, Wolfgang, Van Deventer, E, Bogaards Johannes A, Freek Cox, Wilfred E Marissen, Els van Deventer, Joseph S M Peiris, Chow, Tak-Kwong Vincent, Bakker, Arjen Q., Leung, CSW, Chow, Vincent T., de Kruif, John, Goudsmit Jaap, ter Meulen, Jan, Deventer, Els van, Kruif, John de, De Kruif, J, John de Kruif, Cynthia S W Leung, Jan ter Meulen, Bogaards, Johannes A., Cox, F, Preiser Wolfgang, Cox, Freek, Goudsmit, J, Peiris Joseph S. M, Poon, LLM, Cheung, CY, Johannes A Bogaards, Doerr, HW, van Deventer Els, Marissen, WE, Bakker Arjen Q, Peiris, Joseph S.M., Poon, Leo L. M., Leung Cynthia S. W, Chow, VT, Edward N van den Brink, Bogaards, JA, Vincent T Chow, Arjen Q Bakker, Poon, Leo L.M., Cheung Chung Y, Van Den Brink, EN, Peiris, Joseph Sriyal Malik, Ter Meulen, J, Leung, Cynthia S. W., Goudsmit, Jaap, Peiris, JSM, Meulen, Jan ter, Bakker, AQ, Preiser, W   +73 more
core   +1 more source