Results 81 to 90 of about 4,841,505 (283)

Acute Cor Pulmonale in COVID-19-Related ARDS

JACC: Case Reports, 2020
Coronavirus disease-19 (COVID-19)-related severe acute respiratory distress syndrome can lead to acute cor pulmonale. We report a case of acute cor pulmonale secondary to severe COVID-19 acute respiratory distress syndrome diagnosed with transesophageal ...
Pierre Huette, MD, Christophe Beyls, MD, Mathieu Guilbart, MD, Guillaume Haye, MD, Fatim-Zahra Najid, MD, Benjamin Mestan, MD, Pierre-Alexandre Roger, MD, Hervé Dupont, MD, PhD, Osama Abou-Arab, MD, PhD, Yazine Mahjoub, MD, PhD   +9 more
doaj   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Severe Acute Respiratory Syndrome and Coronavirus

Infectious Disease Clinics of North America, 2010
Severe acute respiratory syndrome (SARS) is a highly infectious disease with a significant morbidity and mortality. Respiratory failure is the major complication, and patients may progress to acute respiratory distress syndrome. Health care workers are particularly vulnerable to SARS.
Hui, David S.C., Chan, Paul K.S.
openaire   +2 more sources

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Severe Acute Respiratory Syndrome in Children

Pediatric Infectious Disease Journal, 2007
Severe acute respiratory syndrome (SARS) is a febrile, respiratory tract illness caused by infection with the newly identified SARS-associated coronavirus. A notable feature of the 2003 global SARS outbreak was the relative paucity of cases reported among children.
Lauren J, Stockman, Mehran S, Massoudi, Rita, Helfand, Dean, Erdman, Alison M, Siwek, Larry J, Anderson, Umesh D, Parashar   +6 more
openaire   +3 more sources

Severe acute respiratory syndrome in a hemodialysis patient [PDF]

American Journal of Kidney Diseases, 2003
Severe acute respiratory syndrome (SARS) is a highly infective disease caused by a newly identified coronavirus. We described the clinical course of the first long-term hemodialysis patient who developed SARS in the literature, and our experience in performing hemodialysis for this patient. Such patients may present with a less typical clinical picture,
Kwan, B. C H, Li, P. K T, Wang, A. Y M, Szeto, Cheuk Chun, Leung, Chi B.   +4 more
openaire   +3 more sources

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source

Pathology and Pathogenesis of Severe Acute Respiratory Syndrome [PDF]

The American Journal of Pathology, 2007
(Uploaded by Plazi for the Bat Literature Project) Severe acute respiratory syndrome (SARS) is an emerging infectious viral disease characterized by severe clinical manifestations of the lower respiratory tract. The pathogenesis of SARS is highly complex, with multiple factors leading to severe injury in the lungs and dissemination of the virus to ...
Gu, Jiang, Korteweg, Christine
openaire   +3 more sources

The outbreak of SARS at Tan Tock Seng Hospital--relating epidemiology to control. [PDF]

, 2006
INTRODUCTION: The outbreak of severe acute respiratory syndrome (SARS) began after the index case was admitted on 1 March 2003. We profile the cases suspected to have acquired the infection in Tan Tock Seng Hospital (TTSH), focussing on major ...
Heng, Bee-Hoon, Leo, Yee-Sin, Chen, Mark IC, Ang, Brenda SP, Choo, Philip   +4 more
core   +1 more source

Pathogenesis of severe acute respiratory syndrome

Current Opinion in Immunology, 2005
Severe acute respiratory syndrome (SARS) is a zoonotic infectious disease caused by a novel coronavirus (CoV). The tissue tropism of SARS-CoV includes not only the lung, but also the gastrointestinal tract, kidney and liver. Angiotensin-converting enzyme 2 (ACE2), the C-type lectin CD209L (also known L-SIGN), and DC-SIGN bind SARS-CoV, but ACE2 appears
Malik Peiris, JS, Yu, LL
openaire   +4 more sources