Results 61 to 70 of about 657,398 (291)

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Peripheral ischemic limb necrosis (Acro-ischemia) associated with severe COVID-19 patients (COVID-19 limbs): A report of three cases

Lung India, 2021
The association between severe coronavirus disease 2019 and hypercoagulable state was observed in many reports. This may be explained by the presence of hypoxia, severe systemic inflammatory response, immobilization due to intensive care unit (ICU ...
Khaled Khattab, Axel Tobias Kempa, Riza Atas, Harun Asani, Ahmed Ehab   +4 more
doaj   +1 more source

SARS-CoV antibody prevalence in all Hong Kong patient contacts. [PDF]

, 2004
A total of 1,068 asymptomatic close contacts of patients with severe acute respiratory (SARS) from the 2003 epidemic in Hong Kong were serologically tested, and 2 (0.19%) were positive for SARS coronavirus immunoglobulin G antibody. SARS rarely manifests
Law, Y-L, Thomas Tsang, Leung, Pak-Yin, Chau, P, Ghani, Azra C, Law, YL, Pak-Yin Leung, Ghani, AC, Lam, TH, Alex Fu, Lam, Tai-Hing, Chan, SKK, Fraser, C, Ng, T, Peiris, JS Malik, Law, Yuk-lung, Donnelly, CA, Ng, Tonny, Fu, Alex, Hedley, AJ, Patsy Chau, Chung, PH, Pui-Hong Chung, Christl A. Donnelly, Anderson, Roy M, Steve K.K. Chan, Chung, Pui-Hong, Riley, Steven, Hedley, Anthony J, Anthony J. Hedley, Chan, Steve KK, Lam, T-H, J.S. Malik Peiris, Tsang, T, Tsang, Thomas, Wilina Lim, Tina Mok, Leung, Gabriel M, Tonny Ng, Christophe Fraser, Anderson, RM, Lim, Wilina, Chau, Patsy, Azra C. Ghani, Mok, Tina, Lim, W, Leung, GM, Ferguson, Neil M, Fraser, Christophe, Mok, T, Leung, PY, Yuk-lung Law, Ferguson, NM, Roy M. Anderson, Fu, A, Tai-Hing Lam, Leung, P-Y, Donnelly, Christi A, Chung, P-H, Steven Riley, Riley, S, Peiris, JSM, Neil M. Ferguson, Gabriel M. Leung   +63 more
core   +1 more source

Severe acute respiratory syndrome in children [PDF]

Pediatric Pulmonology, 2003
AbstractSevere acute respiratory syndrome (SARS) is a newly described and highly contagious respiratory infection. Many adult patients will develop progressive hypoxia, and a large proportion will develop respiratory distress syndrome (RDS), possibly related to massive and uncontrolled activation of the immune system. The mortality has been reported to
Gary W K, Wong, Albert M, Li, P C, Ng, Tai F, Fok   +3 more
openaire   +2 more sources

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

The SARS-coronavirus-host interactome [PDF]

, 2011
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to ...
Brunn, Albrecht von, Steffen, Imke, Kögl, Manfred, Schwegmann-Wessels, Christel, Pumpor, Ksenia, Müller, Marcel A., Herzog, Petra, Kuri, Thomas, Ditt, Vanessa, Weber, Friedemann, Schwarz, Frank, Pfefferle, Susanne, Schöpf, Julia, Kallies, Stefan, Herrler, Georg, Carbajo-Lozoya, Javier, Zimmer, Ralf, Hilgenfeld, Rolf, Friedel, Caroline C., Dall'Armi, Ekatarina von, Drosten, Christian, Niemeyer, Daniela, Thiel, Volker, Züst, Roland, Stellberger, Thorsten, Thiel, Heinz-Jürgen, Pöhlmann, Stefan, Haas, Juergen G.   +27 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Acute pancreatitis following SARS-CoV-2 infection: A case report

SAGE Open Medical Case Reports, 2023
The novel coronavirus 2019 (COVID-19) which is caused by severe acute respiratory syndrome coronavirus-2 was first reported from Wuhan, China in December 2019. Since then, it has caused global crisis and it still continues to be a Public Health Emergency
Ugyen Choden, Sonam Yangzom, Geeta Pradhan, Pema wangchuk   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Severe acute respiratory syndrome coronavirus-2 Alpha variant (B.1.1.7), original wild-type severe acute respiratory syndrome coronavirus 2, and cytomegalovirus co-infection in a young adult with acute lymphoblastic leukemia, case report, and review of the possible cytomegalovirus reactivation mechanisms

Journal of Medical Case Reports, 2023
Background Like other viral infections, severe acute respiratory syndrome coronavirus-2 infection could affect different human body systems, including host immune responses. Three years after its pandemic, we learn more about this novel coronavirus.
Ali Amanati, Mahdi Shahriari, Mohammad Reza Bordbar, Seyyed Bozorgmehr Hedayati, Mazyar Ziyaeyan, Marzieh Jamalidoust, Mehdi Kalani, Nahid Heydari Marandi   +7 more
doaj   +1 more source