Results 101 to 110 of about 622,897 (403)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling

bioRxiv, 2020
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has quickly spread worldwide and has affected more than 10 million individuals.
Yi Zheng, Meng-Wei Zhuang, Lulu Han, Jing Zhang, Mei-Ling Nan, Chengjiang Gao, Peihui Wang   +6 more
semanticscholar   +1 more source

Interleukin-6 Is a Biomarker for the Development of Fatal Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia

Frontiers in Immunology, 2021
Hyper-inflammatory responses induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are a major cause of disease severity and death. Predictive prognosis biomarkers to guide therapeutics are critically lacking.
André Santa Cruz, Ana Mendes-Frias, A. I. Oliveira, Luís Dias, A. R. Matos, Alexandre Carvalho, C. Capela, J. Pedrosa, A. Castro, Ricardo Silvestre   +9 more
semanticscholar   +1 more source

Predicting the recombination potential of severe acute respiratory syndrome coronavirus 2 and Middle East respiratory syndrome coronavirus [PDF]

Journal of General Virology, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recently emerged to cause widespread infections in humans. SARS-CoV-2 infections have been reported in the Kingdom of Saudi Arabia, where Middle East respiratory syndrome coronavirus (MERS-CoV) causes seasonal outbreaks with a case fatality rate of ~37 %.
Banerjee, Arinjay, Doxey, Andrew C., Tremblay, Benjamin J.-M., Mansfield, Michael J., Subudhi, Sonu, Hirota, Jeremy A., Miller, Matthew S., McArthur, Andrew G., Mubareka, Samira, Mossman, Karen   +9 more
openaire   +2 more sources

Undocumented Migrants Reintroducing COVID-19, Yunnan Province, China

Emerging Infectious Diseases, 2021
To limit the spread of severe acute respiratory syndrome coronavirus 2, the government of China has been monitoring infected travelers and minimizing cold-chain contamination. However, other factors might contribute to recurring outbreaks. We analyze the
Meiling Zhang, Jienan Zhou, Senquan Jia, Xiaonan Zhao, Yaoyao Chen, Yanhong Sun, Zhaosheng Liu, Xiaofang Zhou, Duo Li, Chunrui Luo, Yong Zhang, Violet Magoma Onsongo, Yong Shao, Xiaoqing Fu   +13 more
doaj   +1 more source

Neurological symptoms, manifestations, and complications associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19)

Journal of Neurology, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, is responsible for the outbreak of coronavirus disease 19 (COVID-19) and was first identified in Wuhan, China in December 2019.
B. Harapan, H. Yoo
semanticscholar   +1 more source

Structural Proteins in Severe Acute Respiratory Syndrome Coronavirus-2

Archives of Medical Research, 2020
What began with a sign of pneumonia-related respiratory disorders in China has now become a pandemic named by WHO as Covid-19 known to be caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The SARS-CoV-2 are newly emerged β coronaviruses belonging to the Coronaviridae family.
Satarker, Sairaj, Nampoothiri, Madhavan
openaire   +2 more sources

Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 in Aerosol Suspensions

Emerging Infectious Diseases, 2020
We aerosolized severe acute respiratory syndrome coronavirus 2 and determined that its dynamic aerosol efficiency surpassed those of severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome. Although we performed experiment only
Alyssa C. Fears, William B. Klimstra, Paul Duprex, Amy Hartman, Scott C. Weaver, Kenneth S. Plante, Divya Mirchandani, Jessica Ann Plante, Patricia V. Aguilar, Diana Fernández, Aysegul Nalca, Aysegul Totura, David Dyer, Brian Kearney, Matthew Lackemeyer, J. Kyle Bohannon, Reed Johnson, Robert F. Garry, Doug S. Reed, Chad J. Roy   +19 more
doaj   +1 more source

Predicting Infectious Severe Acute Respiratory Syndrome Coronavirus 2 From Diagnostic Samples

Clinical Infectious Diseases, 2020
Reverse-transcription polymerase chain reaction (RT-PCR) has become the primary method to diagnose viral diseases, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
J. Bullard, Kerry Dust, D. Funk, J. Strong, D. Alexander, L. Garnett, Carl Boodman, A. Bello, A. Hedley, Zachary Schiffman, Kaylie Doan, N. Bastien, Yan Li, P. V. Van Caeseele, G. Poliquin   +14 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Replication of Severe Acute Respiratory Syndrome Coronavirus 2 in Human Respiratory Epithelium

Journal of Virology, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged by the end of 2019 and rapidly spread in 2020. At present, it is of utmost importance to understand the biology of the virus, rapidly assess the treatment potential of existing drugs, and develop new active compounds.
Milewska, Aleksandra, Kula-Pacurar, Anna, Wadas, Jakub, Suder, Agnieszka, Szczepanski, Artur, Dabrowska, Agnieszka, Owczarek, Katarzyna, Marcello, Alessandro, Ochman, Marek, Stacel, Tomasz, Rajfur, Zenon, Sanak, Marek, Labaj, Pawel, Branicki, Wojciech, Pyrc, Krzysztof   +14 more
openaire   +5 more sources