COVID-19 Infection: Implications for Perioperative and Critical Care Physicians. [PDF]
Healthcare systems worldwide are responding to Coronavirus Disease 2019 (COVID-19), an emerging infectious syndrome caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus. Patients with COVID-19 can progress from asymptomatic or
Greenland, John R+3 more
core
Computational evidence on repurposing the anti-influenza drugs baloxavir acid and baloxavir marboxil against COVID-19 [PDF]
The main reasons for the ongoing COVID-19 (coronavirus disease 2019) pandemic are the unavailability of recommended efficacious drugs or vaccines along with the human to human transmission nature of SARS-CoV-2 virus. So, there is urgent need to search appropriate therapeutic approach by repurposing approved drugs.
arxiv
Preeclampsia treatment in severe acute respiratory syndrome coronavirus 2 [PDF]
Joudi, Noor+3 more
openaire +2 more sources
Structural basis of severe acute respiratory syndrome coronavirus 2 infection
Purpose of review The spike glycoprotein plays a critical role in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by recognizing the angiotensin converting enzyme 2 (ACE2) receptor and mediating fusion of the viral envelope with the cell membrane.
Ge, Jiwan+3 more
openaire +3 more sources
SARS-CoV-2 Coronavirus Data Compression Benchmark [PDF]
This paper introduces a lossless data compression competition that benchmarks solutions (computer programs) by the compressed size of the 44,981 concatenated SARS-CoV-2 sequences, with a total uncompressed size of 1,339,868,341 bytes. The data, downloaded on 13 December 2020, from the severe acute respiratory syndrome coronavirus 2 data hub of ncbi.nlm.
arxiv
The hallmarks of COVID-19 disease.
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that has caused a worldwide pandemic of the human respiratory illness COVID-19, resulting in a severe threat to public health and safety.
Daolin Tang, Paul Comish, Rui Kang
doaj +1 more source
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) [PDF]
Saak V. Ovsepian+2 more
openaire +3 more sources
Coronavirus in Continuous Flux: From SARS‐CoV to SARS‐CoV‐2
The world is currently experiencing a global pandemic caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which causes severe respiratory disease similar to SARS.
Yetian Dong+4 more
doaj +1 more source
Decoding SARS-CoV-2 transmission, evolution and ramification on COVID-19 diagnosis, vaccine, and medicine [PDF]
Tremendous effort has been given to the development of diagnostic tests, preventive vaccines, and therapeutic medicines for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much of this development has been based on the reference genome collected on January 5, 2020.
arxiv
Repositioning of 8565 existing drugs for COVID-19 [PDF]
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected near 5 million people and led to over 0.3 million deaths. Currently, there is no specific anti-SARS-CoV-2 medication. New drug discovery typically takes more than ten years.
arxiv