Results 231 to 240 of about 28,111,627 (303)

Phase IIB, Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID‐19

European Journal of Haematology, Volume 117, Issue 4, Page 922-935, October 2026.
ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio, Antonio José Martinez‐Mellado, Jonathan Kiwitt‐Cárdenas, José G. Clavel, Bartolomé García‐Perez, Pedro Castro, Maribel Diaz‐Ricart, Andrés Carrillo‐Alcaraz, Amparo López‐Bernús, Enrique Bernal Morell, Aychel Roura, Sonia Marín, Francisco‐José Ruiz‐López, Elena Solana‐Martinez, Domingo Martinez‐Baño, Carlos L. Albacete Moreno, Enriqueta Andreu Soler, Adrián Tellez Santoyo, Sara Fernández Méndez, Jose A. Noguera Velasco, Iria Cebreiros Lopez, Andrés Parrilla, Alberto Espuny‐Miró, David García‐Bernal, Miguel Blanquer, Andrés Sánchez‐Salinas, Francisca Iniesta, Cristina Hernandez Garcia, Manuel Muro, Alfredo Minguela Puras, Antonio Moreno‐Docón, Alberto M. Torres‐Cantero, Maria Munoz Garcia, Manuel Serrano, Massimo Iacobelli, Carmelo Carlo‐Stella, Lee‐Jen Wei, Paul G. Richardson, José M. Moraleda   +38 more
wiley   +1 more source

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Encephalitis With Cerebrospinal Fluid Polymerase Chain Reaction (PCR) Positivity and Normal Neuroimaging: A Case Report. [PDF]

Cureus
Dias G, Franco AI, Santos MG, Graveto C, Araújo A.   +4 more
europepmc   +1 more source

Sulfonic Ion‐Exchange Resins as Versatile Tools for the Oxidative Degradation of Chemical and Biological Hazardous Agents

ChemSusChem, Volume 19, Issue 17, 14 September 2026.
Hydrogen peroxide (H2O2) activation endows sulfonic ion‐exchange resins with synergistic Brønsted acidity and surface‐immobilized oxidants. Activated Amberlyst 15 promotes degradation of 2‐chloroethyl ethyl sulfide (2‐CEES) and malathion while rapidly inactivating Escherichia coli (E. coli), Staphylococcus aureus (S.
Stefano Econdi, Alessandro Caselli, Simona Tomaselli, Laura Ragona, Davide Mileto, Matteo Guidotti   +5 more
wiley   +1 more source

Structure-Based Rational Design of a Selective Hydrolase Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus-2 Nsp3 Macrodomain. [PDF]

Chembiochem
Krishnathas R, Mineev KS, Fourkiotis NK, Touret F, Sideras-Bisdekis C, Tsika AC, Gande SL, Linhard V, Sreeramulu S, Lennartz F, Weiss MS, Coutard B, Spyroulias GA, Schwalbe H.   +13 more
europepmc   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Application of oral fluid for quantitative nucleic acid and antibody detection of the severe acute respiratory syndrome coronavirus 2. [PDF]

Front Public Health
Song R, Li J, Wang Y, Huang Q, Geng Y, Ding X, Duan X, Wen C, Tang Y, Kang L, Huang F, Dong M, Dong J, Chen X.   +13 more
europepmc   +1 more source

Risk of venous thromboembolism after SARS‐CoV‐2 vaccination—Evidence from genome‐wide association study and population‐based observational study

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3246-3256, September 2026.
Aim We aimed to investigate whether genetic variation is associated with venous thromboembolism after immunization with SARS‐CoV‐2 vaccines. Methods We conducted a genome‐wide association study (GWAS) on cases of venous thromboembolism within 42 days after SARS‐CoV‐2 vaccination, recruited from reports of adverse drug reactions sent to the Swedish ...
Sofia Attelind, Niclas Eriksson, Marco Cavalli, Yiyi Xu, Fredrik Nyberg, Anders Sundström, Mia Wadelius, Pär Hallberg   +7 more
wiley   +1 more source

Noninvasive Monitoring of Inflammatory Processes by Myeloid Cell-Directed PET Tracers in an Experimental Severe Acute Respiratory Syndrome Coronavirus 2 Infection Model. [PDF]

J Nucl Med
Stammes MA, Koopman G, Wagner TR, Traenkle B, Kaiser PD, Mooij P, van der Werff N, Acar RF, Böszörményi KP, Blaess S, Pezzana S, Reischl G, Maurer A, Langermans JAM, Rothbauer U, Kneilling M, Sonanini D.   +16 more
europepmc   +1 more source

Digital Management and Service Optimization of Local Library Collections by Deep Learning Algorithms

Engineering Reports, Volume 8, Issue 9, September 2026.
The study proposes a knowledge‐enhanced multi‐field attention model (KEMFA) for local document classification. ABSTRACT This study addressed the digital management and service optimization of local library collections. A KEMFA (Knowledge‐Enhanced Multi‐Field Attention) model was proposed for local document classification.
Jingtao Yu
wiley   +1 more source

Severe acute respiratory syndrome coronavirus 2 and preterm birth, clinical implications-A register-based cohort study from Sweden. [PDF]

Pregnancy (Hoboken)
Berglin L, Källén K, Jacobsson B, Sengpiel V.   +3 more
europepmc   +1 more source