Results 81 to 90 of about 483,790 (291)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Angiotensin-Converting Enzyme Inhibitor / Angiotensin II Receptor Blocker in COVID-19: a Double-edged Sword or a Myth

Nepalese Medical Journal, 2020
Angiotensin-converting enzyme-2 receptor has been unearthed as a prime site of entry of Severe Acute Respiratory Syndrome Coronavirus 2 owing to its strong affinity towards spike protein of Severe Acute Respiratory Syndrome Coronavirus 2, resulting in ...
Kunal Bikram Shaha, Ashok Adhikari, Jung Rae Cho, Bimal Pandey, Yubaraj Sharma, Sajjad Safi   +5 more
doaj   +1 more source

Immune characteristics of human immunodeficiency virus/severe acute respiratory syndrome coronavirus 2 coinfection: A case report and mini-review

SAGE Open Medical Case Reports, 2021
Since its first appearance in Wuhan, China, severe acute respiratory syndrome coronavirus 2 has rapidly spread throughout the world and has become a global pandemic.
Aimei Liu, Jie Wei, Yuanlong Xu, Dayong Huang, Kangyan Lv, Zhihao Meng, Junli Huang, Liling Huang, Guowei Wu   +8 more
doaj   +1 more source

Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study. [PDF]

, 2020
BackgroundAn outbreak of COVID-19 in Iran has spread throughout the country. Identifying the epidemiological characteristics of this disease will help to make appropriate decisions and thus control the epidemic. The aim of this study was characterization
Abbaszadeh, Sepideh, Alimohamadi, Yousef, Alishiri, GholamHossein, Bagheri, Mahdi, Dorostkar, Ruhollah, Ebrahimnia, Mehdi, Farnoosh, Gholamreza, Gouvarchin Ghaleh, Hadi Esmaeili, Heydari, Soleyman, Hosseini Zijoud, Seyed Reza, Izadi, Morteza, Jafari, Nematollah Jonaidi, Jalali Farahani, Alireza, Nikpouraghdam, Mohamad, Qazvini, Ali, Samadinia, Hossein, Sepandi, Mojtaba, Shahriary, Alireza, Taghdir, Maryam, Tat, Mahdi   +19 more
core   +1 more source

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

Advanced Functional Materials, EarlyView.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya, Konda Reddy Kunduru, Krishanu Ghosal, Luna Rizik, Nofar Atari, Mahran Daifa, Neta Kutner, Bassma Khamaisi, Qi Wu, Simran Jindal, Merna Shaheen‐Mualim, Ranabir Majumder, Mahitosh Mandal, Michal Mandelboim, Shady Farah   +14 more
wiley   +1 more source

Bordetella hinzii Pneumonia and Bacteremia in a Patient with SARS-CoV-2 Infection

Emerging Infectious Diseases, 2021
Patients with severe acute respiratory syndrome coronavirus 2 infection may have bacterial co-infections, including pneumonia and bacteremia. Bordetella hinzii infections are rare, may be associated with exposure to poultry, and have been reported mostly
Michele Maison-Fomotar, Geetha Sivasubramanian   +1 more
doaj   +1 more source

Identification of individuals with gonorrhoea within sexual networks: a population-based study.

, 2006
BACKGROUND: Molecular typing of Neisseria gonorrhoeae and contact tracing provide a combined approach for analysis of sexual networks in metropolitan areas, although there are some difficulties in application.
Bishop, Cynthia J, Choudhury, Bhudipa, Fenton, Kevin A, Ghani, Azra C, Ison, Catherine A, Risley, Claire L, Spratt, Brian G, Ward, Helen   +7 more
core   +1 more source

Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns [PDF]

, 2016
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A., Omrani, Ali S.   +2 more
core   +1 more source

Inactivating SARS‐CoV‐2 Virus with MOF‐Composites as Smart Face Masks

Advanced Functional Materials, EarlyView.
In situ preparation and functionalization of MOF@Cotton fabrics as smart face masks for the immobilization of proteins and inactivation viruses, such as SARS‐CoV‐2. Abstract The significant impact of the SARS‐CoV‐2 (COVID‐19) pandemic outbreak on people's lives has highlighted the urgent need for effective personal protective equipment.
Romy Ettlinger, Aamod V. Desai, Hau Lam Jody Cheong, Louise L. Major, Terry K. Smith, Aaron B. Naden, Jane Hilton, Catherine S. Adamson, A. Robert Armstrong, Russell E. Morris   +9 more
wiley   +1 more source

Rhabdomyolysis as Potential Late Complication Associated with COVID-19

Emerging Infectious Diseases, 2020
We describe a patient in Wuhan, China, with severe acute respiratory syndrome coronavirus 2 infection who had progressive pulmonary lesions and rhabdomyolysis with manifestations of lower limb pain and fatigue.
Min Jin, Qiaoxia Tong
doaj   +1 more source