Results 371 to 380 of about 3,446,938 (405)
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The American Journal of the Medical Sciences, 2000
Asthma responds to conventional therapy in the majority of patients. However, attention has recently focused on the 1 to 15% of asthmatics who are thought to manifest severe asthma, which responds poorly to commonly used regimens. In this review, current knowledge about the pathogenesis of severe asthma is reviewed and several distinct clinical ...
Norman M. Kaplan +2 more
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Asthma responds to conventional therapy in the majority of patients. However, attention has recently focused on the 1 to 15% of asthmatics who are thought to manifest severe asthma, which responds poorly to commonly used regimens. In this review, current knowledge about the pathogenesis of severe asthma is reviewed and several distinct clinical ...
Norman M. Kaplan +2 more
openaire +3 more sources
Severe asthma—A population study perspective
Clinical and Experimental Allergy, 2019Severe asthma is a considerable challenge for patients, health‐care professionals and society. Few studies have estimated the prevalence of severe asthma according to modern definitions of which none based on a population study.
H. Backman +9 more
semanticscholar +1 more source
American Review of Respiratory Disease, 1992
Myopathy complicating the therapy of severe asthma has been recently described in several case reports. Twenty-five consecutive patients admitted to the intensive care unit (ICU) at this hospital for mechanical ventilation for severe asthma were studied for the incidence of creatine kinase (CK) enzyme rise and for the development of clinical myopathy ...
Max Weinmann +6 more
openaire +2 more sources
Myopathy complicating the therapy of severe asthma has been recently described in several case reports. Twenty-five consecutive patients admitted to the intensive care unit (ICU) at this hospital for mechanical ventilation for severe asthma were studied for the incidence of creatine kinase (CK) enzyme rise and for the development of clinical myopathy ...
Max Weinmann +6 more
openaire +2 more sources
American Journal of Respiratory and Critical Care Medicine, 1999
The National Asthma Education and Prevention Program (NAEPP) Expert Panel II recommended a stepped care pharmacotherapy approach to asthma treatment based on an objective assessment of asthma severity using daytime symptoms, nocturnal symptoms, and physiologic lung function. The worst grade of the individual variables determines overall asthma severity.
Patti Stampone +4 more
openaire +3 more sources
The National Asthma Education and Prevention Program (NAEPP) Expert Panel II recommended a stepped care pharmacotherapy approach to asthma treatment based on an objective assessment of asthma severity using daytime symptoms, nocturnal symptoms, and physiologic lung function. The worst grade of the individual variables determines overall asthma severity.
Patti Stampone +4 more
openaire +3 more sources
Chest, 2003
Severe asthma is poorly understood clinically, physiologically, and pathologically. While milder forms of asthma are generally easily treated, more severe forms often remain refractory to the best current medical care. Although some patients with severe asthma have had severe disease for most of their lives, there appears to be a second group that ...
openaire +3 more sources
Severe asthma is poorly understood clinically, physiologically, and pathologically. While milder forms of asthma are generally easily treated, more severe forms often remain refractory to the best current medical care. Although some patients with severe asthma have had severe disease for most of their lives, there appears to be a second group that ...
openaire +3 more sources
American Journal of Respiratory and Critical Care Medicine, 2003
Acute severe asthma remains a major economic and health burden. The natural history of acute decompensations is one of resolution and only about 0.4% of patients succumb overall. Mortality in medical intensive care units is higher but is less than 3% of hospital admissions.
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Acute severe asthma remains a major economic and health burden. The natural history of acute decompensations is one of resolution and only about 0.4% of patients succumb overall. Mortality in medical intensive care units is higher but is less than 3% of hospital admissions.
openaire +2 more sources
Paediatric Respiratory Reviews, 2006
Persistent childhood asthma is more common in females with atopy with an early onset and may result in significant impairment of lung function. Pathological changes in severe chronic asthma in childhood are only partially defined and correlation between pathology, response to treatment and persistence is imprecise. Failure to respond to usual therapies
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Persistent childhood asthma is more common in females with atopy with an early onset and may result in significant impairment of lung function. Pathological changes in severe chronic asthma in childhood are only partially defined and correlation between pathology, response to treatment and persistence is imprecise. Failure to respond to usual therapies
openaire +3 more sources
New England Journal of Medicine, 1974
BRONCHIAL asthma, though highly treatable, causes over four thousand deaths annually in the United States. Measures currently available are so effective that control should rarely fail unless the patient delays too long in seeking help or if treatment is not vigorous enough. Functionally, the cardinal feature is airway obstruction, which may be so mild
openaire +3 more sources
BRONCHIAL asthma, though highly treatable, causes over four thousand deaths annually in the United States. Measures currently available are so effective that control should rarely fail unless the patient delays too long in seeking help or if treatment is not vigorous enough. Functionally, the cardinal feature is airway obstruction, which may be so mild
openaire +3 more sources
Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-vornhagen +2 more
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