LDLR-Gene therapy for familial hypercholesterolaemia: Problems, progress, and perspectives [PDF]
Coronary artery diseases (CAD) inflict a heavy economical and social burden on most populations and contribute significantly to their morbidity and mortality rates.
Al-Allaf, FA +5 more
core +3 more sources
Human platelets promote liver regeneration with Kupffer cells in severe combined immunodeficiency mice [PDF]
筑波大学博士 (医学) 学位論文・平成25年3月25日授与 ...
髙橋 一広
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Systemic infections after acute stroke [PDF]
After an acute stroke, systemic infection can complicate the recovery process and lead to a worse clinical outcome, including a higher risk of mortality.
Damian Jenkinson +11 more
core +1 more source
IL7R and RAG1/2 Genes Mutations/Polymorphisms in Patients SCID
SCID disorder is major failure of the immune system, usually genetic. The aim of this study was on mutations detection of RAG1, RAG2, and IL7RG genes in SCID cases. Mutation detection was performed by PCR sequencing.
Sepideh Safaei +3 more
doaj
As a preparatory stage for implementation of genetic testing for severe combined immunodeficiency under a neonatal screening program, a study was performed in Sverdlovsk Region which concerned quantitative determination of T and B cell neogenesis markers
S. S. Deryabina +2 more
doaj +1 more source
TREC Based Newborn Screening for Severe Combined Immunodeficiency Disease: A Systematic Review
BackgroundNewborn screening (NBS) by quantifying T cell receptor excision circles (TRECs) in neonatal dried blood spots (DBS) enables early diagnosis of severe combined immunodeficiency disease (SCID).
J. van der Spek +3 more
semanticscholar +1 more source
Levels of Kappa-deleting recombination excision circles (KRECs), T-cell receptor excision circles (TRECs), and T-cell repertoire diversity were evaluated in 1038 samples of 124 children with primary immunodeficiency, of whom 102 (54 with severe combined ...
Monica Valotti +9 more
doaj +1 more source
Safety and efficacy of colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia as part of a macro-project funded by the Seventh Framework Program of the European Commission studying off-patent antibiotics. study protocol for a randomized controlled trial [PDF]
Background: Ventilator-associated pneumonia (VAP) is one of the most common and severe hospital-adquired infections, and multidrugresistant gram-negative bacilli (MDR-GNB) constitute the main etiology in many countries.
Clara Rosso, Fernández +6 more
core +1 more source
Application of genetically engineered (GE) large animals carrying multi-allelic modifications has been hampered by low efficiency in production and extended gestation period compared to rodents.
Shaohua Lei +12 more
semanticscholar +1 more source
Small bowel and liver/small bowel transplantation in children. [PDF]
A clinical trial of intestinal transplantation was initiated at the University of Pittsburgh in May 1990. Eleven children received either a combined liver/small bowel graft (n = 8) or an isolated small bowel graft (n = 3).
Nour, B +4 more
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