Results 131 to 140 of about 102,336 (247)

Myasthenia Gravis and Thymoma

Muscle &Nerve, EarlyView.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor, Lukas Delasos, Daniel P. Raymond, Erik Seroogy, Jason Lempel, Yuebing Li   +5 more
wiley   +1 more source

X-linked severe combined immunodeficiency due to <i>IL2RG</i> p.V223F variant: clinical evidence that support its pathogenicity- a case report. [PDF]

Front Immunol
Gutiérrez-Zepeda BM, Lona-Reyes JC, Cruz-Muñoz ME, Quintero-Ramos A, Torres-Lozano C, Bayardo-Gutierrez B, Barrón-Balderas A, Rosenzweig SD, Stoddard J, Niemela J, Núñez-Núñez ME.   +10 more
europepmc   +1 more source

Severe Combined Immunodeficiency (SCID) and Its New Treatment Modalities. [PDF]

Cureus, 2023
Wadbudhe AM, Meshram RJ, Tidke SC.
europepmc   +1 more source

Early Remission of Cerebrospinal Fluid Interleukin‐6 After Initial Immunotherapy Predicts a Good Prognosis in Autoimmune Encephalitis

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Background Autoimmune encephalitis therapy requires adjusting the regimen based on therapeutic response; however, clinical indicators of this response remain unknown. Aim To determine the predictive capability of cerebrospinal fluid (CSF), electroencephalography (EEG), and brain magnetic resonance imaging (MRI) in identifying responders to ...
Yuta Madokoro, Yuto Uchida, Hiroyasu Inoue, Toyohiro Sato, Teppei Fujioka, Masayuki Mizuno, Shoji Kawashima, Masahiro Oomura, Noriyuki Matsukawa   +8 more
wiley   +1 more source

Unmanipulated bone marrow infusion without conditioning can rescue <i>RECQL4</i> ^-/- severe combined immunodeficiency. [PDF]

J Hum Immun
Grier AE, Bosticardo M, Pala F, Delmonte OM, Amini K, Anaya E, Romberg N, McClory SE, Bunin NJ, Abdalgani M, Notarangelo LD, Heimall J.   +11 more
europepmc   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Neurodevelopmental outcomes following hematopoietic cell transplantation for patients with severe combined immunodeficiency (SCID): A PIDTC study. [PDF]

J Hum Immun
Brumm VL, Kidd SA, Logan BR, Chunara F, Heimall J, Griffith LM, Kohn DB, Sanchez L, Bednarski JJ, Martinez C, Lugt MV, Kapoor N, Wright N, Spitzer B, Oved JH, Chandra S, Chellapandian D, Ebens CL, Petrovic A, Rayes A, Haines HL, Lust H, Schofield HT, Christopher L, Harris LL, Satter LF, Burroughs L, Dvorak CC, Haddad E, Leiding JW, Marsh RA, Notarangelo LD, Pai SY, Pulsipher MA, Puck JM, Cowan MJ, Shah AJ.   +36 more
europepmc   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Case Report and literature review: X-linked severe combined immunodeficiency complicated by <i>Talaromyces marneffei</i> infection caused by a novel pathogenic <i>IL2RG</i> mutation. [PDF]

Front Pediatr
Qing D, Lin L, Chen F, Peng J.
europepmc   +1 more source

A novel <i>de novo IL2RG</i> nonsense mutation in a pediatric patient with X-linked severe combined immunodeficiency. [PDF]

Front Genet
Wang L, Ren A, He Y, Wang L, Wang S, Xie X, Tan M, Chen Y, Huang P, Du Z.   +9 more
europepmc   +1 more source