ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics +16 more
wiley +1 more source
Hematopoietic stem cell transplantation in a newborn suffering from severe combined immunodeficiency and severe hemophilia A: a case report and review of the literature. [PDF]
Schober S +5 more
europepmc +1 more source
RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run +7 more
wiley +1 more source
The clinical and socioeconomic aspects of t-cell receptor excision circle based newborn screening for severe combined immunodeficiency in Southeast and East Asia. [PDF]
Yoo N +5 more
europepmc +1 more source
Boron‐10 carriers and their applications in boron neutron capture therapy
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang +7 more
wiley +1 more source
Fetal bone engraftment reconstitutes the immune system in pigs with severe combined immunodeficiency. [PDF]
Monarch K +16 more
europepmc +1 more source
Bacillus thuringiensis and its pest control potential as endophyte
Bacillus thuringiensis (Bt) systemically colonizes tomato plants as endophyte, inducing midgut damage, fitness reduction and immune suppression in Spodoptera littoralis larvae feeding on Bt‐colonized leaves. The immune suppression enhances the susceptibility to Bt treatments, allowing a synergistic dual use of Bt commercial formulations, by combined ...
Maria Giovanna De Luca +8 more
wiley +1 more source
Thymic and T-cell intrinsic critical roles associated with severe combined immunodeficiency and Omenn syndrome due to a heterozygous variant (G201R) in PSMB10. [PDF]
Kuehn HS +15 more
europepmc +1 more source
Unilateral Freezing of Gait in Normal Pressure Hydrocephalus after Stroke
Movement Disorders Clinical Practice, EarlyView.
Jose Portales +2 more
wiley +1 more source
Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux +6 more
wiley +1 more source

