Results 251 to 260 of about 180,819 (342)

Case report: A novel <i>JAK3</i> homozygous variant in a patient with severe combined immunodeficiency and persistent COVID-19. [PDF]

Front Immunol
Sbruzzi RC, Prado MJ, Fam B, Prolla HA, Hellwig A, Motta Rodrigues G, de-Paris F, Jobim M, Artigalás O, Seeleuthner Y, Casanova JL, Bustamante J, Vianna FSL.   +12 more
europepmc   +1 more source

An Integrated Method to Evaluate the Treatment Efficacy and Immunogenicity of B‐Cell Acute Lymphoblastic Leukemia Therapeutic Enzyme Formulations

Small Methods, EarlyView.
This work presents an integrated set of methods to evaluate the efficacy of asparaginase formulations against B‐cell Acute Lymphoblastic Leukemia (ALL) in mice, including the establishment of an ALL murine model, an amino acid depletion study using high‐performance liquid chromatography (HPLC), and comprehensive assessment of antibody production ...
Julien Santelli, Annie Y. Heble, Connor Endsley, Adam Woodward, Nazia Hafeez, Naomi Winick, Jacques Lux   +6 more
wiley   +1 more source

Corrigendum: Abnormalities of thymic stroma may contribute to immune dysregulation in murine models of leaky severe combined immunodeficiency. [PDF]

Front Immunol
Rucci F, Poliani PL, Caraffi S, Paganini T, Fontana E, Giliani S, Alt FW, Notarangelo LD.   +7 more
europepmc   +1 more source

Alterations of the oral microbiome in patients reinfected with SARS‐CoV‐2 omicron variants

VIEW, EarlyView.
We studied the oral microbiome (the community of microbes in the mouth) in people who were reinfected with the omicron variant of SARS‐CoV‐2 and compared it with healthy individuals and other respiratory illness groups. By sequencing tongue‐coating samples from large cohorts, we identified microbial shifts linked to Omicron reinfection and built a ...
Benchen Rao, Yongjian Zhou, Tong Ren, Hongxia Liang, Lei Li, Yakun Xu, Haiyu Wang, Xiaoping Wang, Xiaoli Ni, Xiaoning Wang, Hanmeng Liu, Xiaoli Jin, Qiaoxia Chen, Xuemei Wang, Yawen Zou, Ying Sun, Zhigang Ren, Zujiang Yu   +17 more
wiley   +1 more source

HIV-1 and SIV Infection are associated with early loss of lung interstitial CD4+ T cells and dissemination of pulmonary tuberculosis [PDF]

, 2019
et al,, Khader, Shabaana A
core   +1 more source

Family History of Early Infant Death Correlates with Earlier Age at Diagnosis But Not Shorter Time to Diagnosis for Severe Combined Immunodeficiency

, 2017
Anderson Dik Wai Luk, Pamela Lee, Huawei Mao, Kin Wai Chan, Xiang-Yuan Chen, Tongxin Chen, Jian He, Nadia Kechout, Deepti Suri, Yin Bo Tao, Yong Xu, Jiang Li, Woei Kang Liew, Orathai Jirapongsananuruk, Tassalapa Daengsuwan, Anju Gupta, Surjit Singh, Amit Rawat, Amir Hamzah Abdul Latiff, Acw Lee, Lynette Pei‐Chi Shek, Nguyen Ngoc Quynh Le, Tek Jee Chin, Yin‐Hsiu Chien, Zarina Abdul Latiff, Thi Minh Huong Le, Nguyen Ngoc Quynh Le, Bee Wah Lee, Qiang Li, Dinesh Raj, Mohamed‐Ridha Barbouche, Meow‐Keong Thong, Maria Carmen D. Ang, Xiao-Chuan Wang, Chuanlong Xu, Hai Guo Yu, Hsin‐Hui Yu, Tsz Leung Lee, Felix Yat Sun Yau, Wilfred Hing Sang Wong, Wenwei Tu, Wu Yang, Patrick Chun Yin Chong, M. Ho, YL Lau   +44 more
openalex   +1 more source

Solamargine induces acute myeloid leukemia differentiation through TLR8 activation

VIEW, EarlyView.
SM, a steroidal alkaloid from Solanum nigrum L. has shown anticancer effect on various kinds of human cancer cells, yet its effect on leukemia cells remains unclear. This study examines antileukemic activities of SM in AML cells. Results indicate SM inhibits growth and promotes apoptosis of AML cells.
Qiaoyan Han, Yuting Chen, Zheyi Li, Yonglin Peng, Zhehan Hu, Yuliang Deng, Yanli Fu, Ming Cheng, Sheng Tan, Jing Tian, Xiaodong Zhao, Miao Sun   +11 more
wiley   +1 more source

A case of severe combined immunodeficiency presented with antibiotic treatment resistant pneumonia and respiratory failure

, 2013
Fumito Nakamura, Yoji Otsuka, Tatsuya Nagano, Takashi Igarashi, Naoyuki Taga, Mamoru Takeuchi   +5 more
openalex   +2 more sources

Clinical Features and Outcomes of Chronic Otitis Media Complications: A 20‐Year Retrospective Study at a Tertiary Hospital

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Chronic otitis media (COM) is a major public health concern, particularly in developing countries. Although complications have decreased with modern antibiotics, they still cause significant morbidity and mortality. This study analyzed the clinical features, bacteriological profiles, and treatment outcomes of COM complications at a ...
Viraporn Atchariyasathian, Nipit Tangchitnob   +1 more
wiley   +1 more source

Development of a novel rodent model for dog heartworm microfilaremia using the severe-combined immunodeficiency mouse. [PDF]

Sci Rep
Mizuseki M, Ikeda N, Shirozu T, Yamagishi M, Oshiro S, Fukumoto S.   +5 more
europepmc   +1 more source