Results 291 to 300 of about 180,819 (342)

Severe Combined Immunodeficiency Disorders

Immunology and Allergy Clinics of North America, 2015
Severe combined immunodeficiency disorders represent pediatric emergencies due to absence of adaptive immune responses to infections. The conditions result from either intrinsic defects in T-cell development (ie, severe combined immunodeficiency disease [SCID]) or congenital athymia (eg, complete DiGeorge anomaly).
Ivan K, Chinn, William T, Shearer
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Severe Combined Immunodeficiency Diseases

Springer Seminars in Immunopathology, 1978
The most severe, and also a relatively common immunodeficiency syndrome involves both antibody- and cell-mediated immune mechanisms. In more modern terms the ‘severe combined immunodeficiency’ syndromes (SCID) are defined as all diseases resulting from marked and longlasting functional impairment of both the T- and B-cell system.
W. H. Hitzig, L. J. Dooren, J. M. Vossen
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X-linked severe combined immunodeficiency

Clinical Immunology and Immunopathology, 1991
Between a third and half of all males with SCID and no family history of immunodeficiency represent the first manifestation in their family of a new mutation of the gene that causes X-linked SCID. These patients, like boys with a positive family history of X-linked SCID, have markedly reduced numbers of T cells, elevated numbers of B cells, and ...
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Severe Combined Immunodeficiency Disease

JAMA, 1977
Pretransplant and posttransplant data for 69 patients with severe combined immunodeficiency disease are presented. Both B and T lymphocyte functions were absent in approximately 80% of the children and markedly depressed in the remainder. Transplantation of marrow from HLA genotypically identical donors provided the highest six-month survival rate (63%)
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Severe combined immunodeficiencies.

Immunodeficiency reviews, 1992
Severe combined immunodeficiencies (SCID) represent an heterogeneous group of diseases characterized by a profound defect in either T cell differentiation or function. The molecular nature of the defect has so far been defined for a small number of SCID, i.e. purin metabolism enzyme deficiencies.
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Domestic animal models of severe combined immunodeficiency: canine X-linked severe combined immunodeficiency and severe combined immunodeficiency in horses.

Immunodeficiency reviews, 1993
This review describes the clinical, immunologic and pathologic features of two naturally-occurring models of severe combined immunodeficiency (SCID) in domestic animals that represent different forms of human SCID. Canine X-linked SCID (XSCID) has an X-linked recessive mode of inheritance and, as such, represents a model for the most common form of ...
P J, Felsburg, R L, Somberg, L E, Perryman   +2 more
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Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Boris Böll, Victoria Metaxa   +2 more
exaly  

Severe Combined Immunodeficiency Disease

2011
Militsakh, O., Day, T., Hornig, J., Lentsch, E., Skoner, J., Gillespie, M., Sharma, A., Neville, B., Rumboldt, Z., James, R., Goddard, J., Shikata, K., Doi, Y., Rosen, E. M., Goldberg, I. D., Fan, S., Kong, L., Lu, J. J., Chlenski, A., Cohn, S. L., Hlubek, F., Qian, C.-N., Teh, B. T., Batistatou, A., Charalbopoulos, K., Christensen, C., Reddel, R., Ploeg, I. M. C., Kroon, B. B. R., Nieweg, O. E., Rijk, M. C., Winqvist, O., Thorn, M., Zwick, C., Pfreundschuh, M., Knudsen, B. S., Lucas, J., Nelson, P., Kashikar, N., Datta, P. K., Hottinger, A. F., Hormigo, A., Knobler, E., Knobler, R., McCarty, J. H., Bardia, A., Loprinzi, C., Buettner, R., Jove, R., Garcia, R., Frank, D. A., Nakatsura, T., Witt, O., Yoshida, K., Chou, P.-L., Tsay, G. J., Takeuchi, T., Furihata, M., Robertson, F. M., Werbowetski-Ogilvie, T. E., Maestro, R. F., Sadr, M. S., Dennler, S., Dijke, P., Gadgeel, S., Tierauch, K.-H., Yip, K. W., Liu, F.-F., Cano, A., Neto, M. A., Rünger, T. M., Frühwald, Michael C., Trakhtenbrot, L., Mi, J., Larner, J. M., Hamlin, J. L., Radin, N. S., Lo, T. L., Guy, G. R., Yeudall, W. A., Parsons, S. J., Fan, F., Platanias, L. C., Mcgahren-Murray, M., Keyomarsi, K., Kos, J., Seigel, G. M., Alison, M. R., Hiyama, E., Renehan, A. G., Potten, C. S., Tang, D. G., Foster, P., Lin, K., Bergelt, C., Ronai, Z., Cukierman, E., Aumercier, M., Hodson, M., Lolis, E., Mehta, A., Chung, F.-L., Glatt, H., Oberthür, A., Warnat, P., Aranda, S., Culig, Z., Chung, B. H., Shin, Y.-B., Kim, M., Grevenstein, W. M. U., van Eijck, C. H. J., Baker, S. G., Kramer, B. S., Mahotka, C., Carbone, M., Yang, H., Mueller, S. C., Coopman, P. J., Brujin, D., Kessel, A. D., George, J. M.   +121 more
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