Results 41 to 50 of about 501,602 (328)
Mixed models for longitudinal left-censored repeated measures [PDF]
Longitudinal studies could be complicated by left-censored repeated measures. For example, in Human Immunodeficiency Virus infection, there is a detection limit of the assay used to quantify the plasma viral load. Simple imputation of the limit of the detection or of half of this limit for left-censored measures biases estimations and their standard ...
arxiv +1 more source
Abstract Objective A substantial part of central nervous system (CNS) disorders remains unexplained, despite various new and minimally invasive diagnostic techniques. Within this rapidly developing diagnostic field, the precise role of brain biopsy is unknown.
Robin W. van Steenhoven+14 more
wiley +1 more source
Severe combined immunodeficiency (SCID), the most severe form of T cell immunodeficiency, is detectable through quantification of T cell receptor excision circles (TRECs) in dried blood spots obtained at birth.
Erez Rechavi+27 more
doaj +1 more source
Mice with severe combined immunodeficiency are commonly used as hosts of human cells. Size, longevity, and physiology, however, limit the extent to which immunodeficient mice can model human systems.
Renan B. Sper+24 more
doaj +1 more source
Integrating selective RNA shortcut, targeted gene isolation, and micro‐arrayed nanoimaging, the NanoPick‐array platform excels in detecting severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) at just 60 copies µL−1 and accurately differentiating variants at the single‐nucleotide level. It ensures 100% accuracy for samples with cycle threshold (
Zixun Wang+9 more
wiley +1 more source
Newborn Screening for Severe Combined Immunodeficiency in Israel
Newborn screening (NBS) programs for severe combined immunodeficiency (SCID), the most severe type of primary immunodeficiency, are being implemented in more and more countries with every passing year.
Erez Rechavi+5 more
doaj +1 more source
Omenn syndrome: the drama of a family, congenital ichthyosis is not always mundane!
Background: The case we are reporting is about one of the rare manifestations of severe combined immunodeficiency, Omenn syndrome (OS). Case presentation: A 43-days-old female presented with thick diffuse erythrodermic scaly ichthyosiform lesions on ...
Massilia Bouhmidi +6 more
doaj +1 more source
Inorganic Nanomaterials Meet the Immune System: An Intricate Balance
Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli+3 more
wiley +1 more source
Abstract Background Survivors of Hodgkin lymphoma (HL) are at risk of developing non‐Hodgkin lymphoma (NHL) after treatment; however, the risks of developing subsequent primary lymphomas (SPLs), including HL and NHL, after different types of childhood cancer are unknown.
Isabelle M. Dudley+38 more
wiley +1 more source
For the recovery or replacement of dysfunctional cells and tissue—the goal of stem cell research—successful engraftment of transplanted cells and tissues are essential events.
Yoon-Young Kim+5 more
doaj +1 more source