Results 41 to 50 of about 178,738 (298)
Peripartum infections and associated maternal mortality in rural Malawi [PDF]
Article approval pendingTo assess associations between maternal mortality and severe morbidity and human immunodeficiency virus (HIV) infection, uptake of antiretroviral therapy, obstetric infections, and nonobstetric infections in a rural Malawian ...
Ahmad +23 more
core +3 more sources
Immunologic aspects of patients with disseminated bacille Calmette-Guerin disease in north-west of Iran [PDF]
International audienceBACKGROUND: Adverse reactions induced by BCG vaccination are rare, disseminated mycobacterial BCG infection in particular, which is often fatal and results from impaired immunity.
Mahnaz Sadeghi-Shanbestari +9 more
core +3 more sources
A Novel Homozygous JAK3 Mutation Leading to T-B+NK– SCID in Two Brazilian Patients
We report a novel homozygous JAK3 mutation in two female Brazilian SCID infants from two unrelated kindreds. Patient 1 was referred at 2 months of age due to a family history of immunodeficiency and the appearance of a facial rash.
Lucila A. Barreiros +6 more
doaj +1 more source
Diagnosis of severe combined immunodeficiency [PDF]
Early diagnosis of severe combined immunodeficiency (SCID) is important to enable prompt referral to a supraregional centre for bone marrow transplantation before the occurrence of end organ damage secondary to infective complications. This review outlines clinical, microbiological, and immunopathological clues that aid the diagnosis of SCID and ...
Gennery AR, Cant AJ
openaire +3 more sources
Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima +18 more
core
Interventions for neurocognitive dysfunction [PDF]
Purpose of review: To evaluate current barriers to HIV cure strategies and interventions for neurocognitive dysfunction with a particular focus on recent advancements over the last three years. Recent findings: Optimal anti-retroviral therapy (ART) poses
Brew, B, Ellero, J, Lubomski, M
core +2 more sources
A high-quality severe combined immunodeficiency (SCID) rat bioresource.
Immunodeficient animals are valuable models for the engraftment of exogenous tissues; they are widely used in many fields, including the creation of humanized animal models, as well as regenerative medicine and oncology.
Yoshiki Miyasaka +7 more
doaj +1 more source
FOXN1 Deficiency: from the Discovery to Novel Therapeutic Approaches [PDF]
Since the discovery of FOXN1 deficiency, the human counterpart of the nude mouse, a growing body of evidence investigating the role of FOXN1 in thymus and skin, has been published.
Cirillo, Emilia +3 more
core +1 more source
Radiosensitive Severe Combined Immunodeficiency Disease [PDF]
Inherited defects in components of the nonhomologous end-joining DNA repair mechanism produce a T-B-NK+ severe combined immunodeficiency disease (SCID) characterized by heightened sensitivity to ionizing radiation. Patients with the radiosensitive form of SCID may also have increased short- and long-term sensitivity to the alkylator-based chemotherapy ...
Christopher C, Dvorak, Morton J, Cowan
openaire +2 more sources

