Results 61 to 70 of about 6,974,500 (303)
Sleep apnoea is a risk factor for severe COVID-19
BMJ Open Respiratory Research, 2021 Background Obstructive sleep apnoea (OSA) is associated with higher body mass index (BMI), diabetes, older age and male gender, which are all risk factors for severe COVID-19.We aimed to study if OSA is an independent risk factor for COVID-19 infection ...
Riitta Kaarteenaho +249 more
doaj +1 more source
Dysregulated Interferon Response Underlying Severe COVID-19
, 2020 Innate immune interferons (IFNs), including type I and III IFNs, constitute critical antiviral mechanisms. Recent studies reveal that IFN dysregulation is key to determine COVID-19 pathogenesis. Effective IFN stimulation or prophylactic administration of
LeAnn Lopez +3 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao +5 more
wiley +1 more source
Calcineurin inhibitors revisited: A new paradigm for COVID-19?
Brazilian Journal of Infectious Diseases, 2020 The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can cause mild, moderate or severe disease (COVID-19). In severe disease, there is hyperinflammation causing severe symptoms.
René Hage +2 more
doaj +1 more source
Biomarkers for severe COVID-19 [PDF]
EBioMedicine, 2021 Xin Li, Kelvin K.W. To
openaire +3 more sources
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Severe peripartum cardiomyopathy complicated by COVID‐19 infection and small intestinal obstruction
Clinical Case Reports, 2021 COVID‐19 infection can be a possible trigger for peripartum cardiomyopathy. Multidisciplinary teamwork was crucial for the favorable outcome in our patient. Small bowel strangulation is a rare complication post‐cesarean section.
Ekhlas Abdulraheem +2 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 BackgroundCoronavirus disease 2019 (COVID-19) has posed a great threat to global public health. There remains an urgent need to address the clinical significance of laboratory finding changes in predicting disease progression in COVID-19 patients.
Man Wang +11 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Dysbiosis of gut microbiota in patients with severe COVID‐19
Acute Medicine & SurgeryAim Altered gut microbiota has been proposed as one of the causes of exacerbation of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2/COVID‐19) from the perspective of the gut–lung axis.
Kentaro Shimizu +10 more
doaj +1 more source