Results 81 to 90 of about 6,974,500 (303)

COVID-19 outcomes in individuals with severe alpha-1 antitrypsin deficiency in Sweden

open access: yesScientific Reports
We have previously found using questionnaire/interview data on COVID-19 outcomes, that most subjects with severe alpha-1-antitrypsin deficiency (AATD) exhibit mild COVID-19 infection and those who additionally have COPD are at increased risk of severe ...
Suneela Zaigham   +2 more
doaj   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong   +10 more
wiley   +1 more source

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

open access: yesArthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan   +10 more
wiley   +1 more source

Tocilizumab for severe COVID-19 pneumonia [PDF]

open access: yesThe Lancet Rheumatology, 2020
Piano S.   +30 more
  +11 more sources

Pulmonary alveolar proteinosis following severe COVID - 19 infection: A case report

open access: yesRespiratory Medicine Case Reports
A 67-year-old male, with a history of severe COVID-19 infection and exposure to talc was seen for worsening shortness of breath for months, requiring supplemental oxygen.
Samina Martin   +2 more
doaj   +1 more source

Immunothrombosis in severe COVID-19 [PDF]

open access: yeseBioMedicine, 2020
Nakazawa, Daigo, Ishizu, Akihiro
openaire   +4 more sources

The Association of Physical Function With Psychosocial Patient‐Reported Outcomes in People With Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts (Approaches to Positive, Patient‐Centered Experiences of Aging with Lupus [APPEAL] and California Lupus Epidemiology Study
Mrinalini Dey   +8 more
wiley   +1 more source

Genetic Risk of Severe Covid-19

open access: yesNew England Journal of Medicine, 2020
The large majority of patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have mild or no symptoms,1 whereas a small proportion of patients have respiratory compromi...
openaire   +3 more sources

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah   +6 more
wiley   +1 more source

Azithromycin for severe COVID-19 [PDF]

open access: yesThe Lancet, 2020
Oldenburg, Catherine E, Doan, Thuy
openaire   +2 more sources

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