Results 121 to 130 of about 2,937,491 (330)

Severe Dengue with Hemophagocytosis Syndrome.

Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia, 2020
Dengue is known to cause high morbidity and mortality worldwide. In recent years, there have been increasing cases of dengue fever associated with a rare complication: hemophagocytic syndrome (HPS), which is a dangerous disorder that carries high mortality. It is associated with infections, autoimmune disorders, and malignancies.
Siti Hartini Ishak, Lili Husniati Yaacob, Azlina Ishak   +2 more
openaire   +2 more sources

“Molecular Docking and Dynamic Studies of Amide Derivatives from Cinnamic Acid with Potential Anti‐Dengue Virus Activity”

ChemistryOpen, EarlyView.
A library of easily synthesizable CAPE analogs was screened in silico against the dengue virus envelope protein. Compound LQM778 showed stable binding and promising inhibitory potential. This study highlights LQM778 as a candidate for future in vitro validation and structural optimization toward accessible antiviral agents against dengue.
Luis Alfonso Cárdenas‐Granados, Manuel Alejandro Hernández‐Serda, Omar Joel Villegas‐Solís, Víctor Hugo Vázquez‐Valadez, Aldo Yoshio Alarcón‐López, Pablo A. Martínez‐Soriano, Jaqueline Ramos‐Sánchez, Tannya Karen Castro‐Jiménez, José Bustos‐Arriaga, Enrique Angeles   +9 more
wiley   +1 more source

Metformin Use and Severe Dengue in Diabetic Adults

Scientific Reports, 2018
Diabetes mellitus is a risk factor for severe dengue in adults, but few studies have examined the association between metformin use and disease severity in dengue.
H. Htun, T. Yeo, C. Tam, J. Pang, Y. Leo, D. Lye   +5 more
semanticscholar   +1 more source

Diagnosis and Prognosis of Severe Dengue [PDF]

, 2011
Dengue has a broad spectrum of clinical symptoms, ranging from asymptomatic infection, undifferentiated fever and dengue fever (DF) to dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). DHF and DSS are the most severe forms of the disease, as they involve bleeding and hypovolemic shock and may lead to death if they are not diagnosed early ...
openaire   +2 more sources

Advancing dengue vaccine development: Challenges, innovations, and the path toward global protection

Pediatric Investigation, EarlyView.
Dengue vaccine development faces challenges, including antibody‐dependent enhancement and serotype‐specific immunity. This review highlights licensed vaccines, CYD‐TDV, TAK‐003, and Butantan‐DV, and explores strategies for achieving effective multivalent protection.
Ran Wang, Bridget Kim, Hridesh Mishra, Kevin C. Kain   +3 more
wiley   +1 more source

Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Accurate biomolecular structure prediction enables the prediction of mutational effects, the speculation of function based on predicted structural homology, the analysis of ligand binding modes, experimental model building, and many other applications.
Rachael C. Kretsch, Reinhard Albrecht, Ebbe S. Andersen, Hsuan‐Ai Chen, Wah Chiu, Rhiju Das, Jeanine G. Gezelle, Marcus D. Hartmann, Claudia Höbartner, Yimin Hu, Shekhar Jadhav, Philip E. Johnson, Christopher P. Jones, Deepak Koirala, Emil L. Kristoffersen, Eric Largy, Anna Lewicka, Cameron D. Mackereth, Marco Marcia, Michela Nigro, Manju Ojha, Joseph A. Piccirilli, Phoebe A. Rice, Heewhan Shin, Anna‐Lena Steckelberg, Zhaoming Su, Yoshita Srivastava, Liu Wang, Yuan Wu, Jiahao Xie, Nikolaj H. Zwergius, John Moult, Andriy Kryshtafovych   +32 more
wiley   +1 more source

Analysis of Gender and Youth Employment in Rwanda [PDF]

, 2014
This study focuses on labor outcomes of women and youth?the former have moved into low-quality employment, while the latter have high rates of underemployment.
Alice Nabalamba, Edward Sennoga
core  

Enhancement of Epidemiological Models for Dengue Fever Based on Twitter Data

, 2017
Epidemiological early warning systems for dengue fever rely on up-to-date epidemiological data to forecast future incidence. However, epidemiological data typically requires time to be available, due to the application of time-consuming laboratorial ...
Albinati, Julio, Marques-Toledo, Cecilia, Meira Jr., Wagner, Pappa, Gisele L., Teixeira, Mauro   +4 more
core   +1 more source

Risk factors associated with death in Brazilian children with severe dengue: a case-control study

Clinics, 2014
Objective: The purpose of this case-control study was to evaluate risk factors associated with death in children with severe dengue. Methods: The clinical condition of hospitalized patients with severe dengue who died (cases, n = 18) was compared with ...
Maria dos Remedios Freitas Carvalho Branco, Expedito Jose de Albuquerque Luna, Leonidas Lopes Braga Junior, Ricardo Villar Barbosa de Oliveira, Livia Teresa Moreira Rios, Maria do Socorro da Silva, Maria Nilza Lima Medeiros, Gilnara Fontinelle Silva, Fernanda Campos Amaral Figueiredo Nina, Taliane Jardim Lima, Jayron Alves Brito, Avessandra Costa Cardoso de Oliveira, Claudio Sergio Pannuti   +12 more
doaj   +1 more source

Dengue and severe dengue with neurological complications: a challenge for prevention and control. [PDF]

Arq Neuropsiquiatr
AbstractDengue is the main urban arbovirus in the Americas. The disease manifests in a varied spectrum: from asymptomatic cases to those with neurological involvement, which is considered a severe form of the disease. Its annual reemergence represents a serious public health problem.
Francelino EO, Puccioni-Sohler M.
europepmc   +4 more sources