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Markers of Dengue Disease Severity
2009Infection with one of the four serotypes of dengue virus (DENV) causes a wide spectrum of clinical disease ranging from asymptomatic infection, undifferentiated fever, dengue fever (DF) to dengue hemorrhagic fever (DHF). DHF occurs in a minority of patients and is characterized by bleeding and plasma leakage which may lead to shock. There are currently
Anon, Srikiatkhachorn, Sharone, Green
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Severe dengue: questioning the paradigm
Microbes and Infection, 2010Severe dengue has been recognised for more than 200 years, but attempts to define, categorize and explain the condition have hotly contested for more than four decades. Resolution of this controversy may provide new insights for the management of patients.
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Risk factors and biomarkers of severe dengue
Current Opinion in Virology, 2020Dengue virus infects several million people each year. Although usually a self-limiting disease, some patients can develop life-threatening severe complications, characterized by plasma leakage, hemorrhaging, and shock. The signs and symptoms of severe disease usually arise late in the disease course when patients are recovering and fever has subsided,
Abhay PS Rathore +2 more
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Ferritin levels predict severe dengue
Infection, 2014Currently, no tests are available to monitor and predict severity and outcome of dengue. To find potential markers that predict dengue severity, the present study validated the serum level of three acute-phase proteins α-1 antitrypsin, ceruloplasmin and ferritin in a pool of severe dengue cases compared to non-severe forms and other febrile illness ...
R, Soundravally +4 more
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Unusual presentation of severe dengue: Dengue maculopathy.
The Medical journal of Malaysia, 2019Dengue infection is epidemic but ocular complications of dengue are less reported. We report a case of dengueinfected patient with disturbing ocular symptoms. He was admitted for severe dengue. Subsequently, he presented with symptoms of bilateral central scotoma with metamorphosia.
K H, Chuah +3 more
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A helping hand against severe dengue
Cell Host & MicrobeWhat immune responses protect against severe dengue? In this issue of Cell Host & Microbe, Gonnella et al. find that early CD4+ TEMRA cell expansion, enhanced regulatory T cell function, and type I IFN signatures in T cells are associated with protection, offering insights with implications for dengue vaccine development.
Shirin Kalimuddin, Eng Eong Ooi
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Glycosylation, diabetes and dengue: Effect on severity?
Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 2011Co-presentation between dengue and diabetes mellitus (DM) can be expected. The author hereby assesses the effect of glycosylation process in poor glycemic control cases on the course of dengue infection.The aim of this work is to assess the effect of glycosylation of CD61 on the pathogenesis of dengue hemorrhagic fever.
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Pediatric Critical Care Medicine, 2012
Christopher J, Gregory, Kay M, Tomashek
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Christopher J, Gregory, Kay M, Tomashek
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Ogilvie's syndrome in severe dengue
The Lancet, 2013Ahmad Mursel, Anam, Raihan, Rabbani
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