Results 181 to 190 of about 327,068 (394)

Clinical and economic consequences of switching from omalizumab to mepolizumab in uncontrolled severe eosinophilic asthma [PDF]

, 2021
Giovanna Elisiana Carpagnano, Emanuela Resta, Massimiliano Povero, Corrado Pelaia, Maria D’Amato, Nunzio Crimi, Nicola Scichilone, Giulia Scioscia, Onofrio Resta, Cecilia Calabrese, Girolamo Pelaia, Maria Pia Foschino Barbaro   +11 more
openalex   +1 more source

Transcriptomic Profiles of the Nasal Mucosa Following Birch Pollen Provocation Differ Between Birch Pollen‐Allergic and Non‐Allergic Individuals

Allergy, EarlyView.
Fourteen genes, mainly encoding keratins, were commonly differentially expressed in both allergic and non‐allergic individuals after nasal provocation with birch pollen. The nasal provocation in birch pollen‐allergic individuals led to activation of innate immune pathways within 15–30 min and proliferation‐regulatory pathways within 60–120 min.
Srinidhi Sudharson, Julia Eckl‐Dorna, Anastasia Meshcheryakova, José Basílio, Sophia Derdak, Tanja Kalic, Nina Lengger, Nina Schweitzer, Diana Mechtcheriakova, Heimo Breiteneder, Christine Hafner   +10 more
wiley   +1 more source

A case of repetitive myocardial infarction with unobstructed coronaries due to Churg-Strauss syndrome [PDF]

, 2019
© The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology.BackgroundMyocardial infarction is most commonly caused by thrombosis occurring on a background of coronary atherosclerosis, resulting in reduced ...
Agewall, Benallegue, Dennert, Fatima, Grodzinsky, Groh, Lanham, Masi, Mukhtyar, Takagi, Tornvall, Trivedi   +11 more
core   +2 more sources

A Case of Severe Asthma with Eosinophilic Otitis Media Successfully Treated with Anti-IgE Monoclonal Antibody Omalizumab [PDF]

, 2012
Azusa Okude, Etsuko Tagaya, Mitsuko Kondo, Manabu Nonaka, Jun Tamaoki   +4 more
openalex   +1 more source

The inflammatory profile of exacerbations in patients with severe refractory eosinophilic asthma receiving mepolizumab (the MEX study): a prospective observational study [PDF]

, 2021
P. Jane McDowell, Sarah Diver, Freda Yang, Catherine Borg, John Busby, Vanessa Brown, Rahul Shrimanker, Ciara Cox, Christopher E. Brightling, Rekha Chaudhuri, Ian Pavord, Liam G. Heaney, P. Jane McDowell, Sarah Diver, Freda Yang, Catherine Borg, John Busby, Vanessa Brown, Rahul Shrimanker, Ciara Cox, Christopher E. Brightling, Rekha Chaudhuri, Ian Pavord, Liam G. Heaney, Christopher M. Wise, Christine McAnally, Stephen Drain, Vijay Mistry, H. Arnold, Claudia Micieli, William Monterio, Marc Jones, Hattie Ellis, Samantha Thulborn, Linda Cheyne, Esther Ramsey, Sarah Howes, Michelle Bourne, Tracy Thorton, Sarah Edwards, Helen Evans, Steven G. Smith, Tracyanne Grandison   +42 more
openalex   +1 more source

Reduction of daily maintenance inhaled corticosteroids in patients with severe eosinophilic asthma treated with benralizumab (SHAMAL): a randomised, multicentre, open-label, phase 4 study

The Lancet, 2023
David J Jackson, L. Heaney, M. Humbert, B. Kent, A. Shavit, Lina Hiljemark, L. Olinger, David Cohen, A. Menzies-Gow, Stephanie Korn, Claus Kroegel, Cristiano Caruso, Ilaria Baglivo, S. Colantuono, David J Jackson, D. Skowasch, Fabiano Di Marco, F. Couturaud, F. Käßner, Iwona Cwiek, Markus Teber, Kornelia Knetsch, Jasmin Preuß, G. Devouassoux, Katrin Milger-Kneidinger, L. Heaney, Lukas Jerrentrup, M. Jandl, Hartmut Timmermann, Beatrice Probst, Maria D’Amato, Martin Hoffmann, Philippe Bonniaud, G. Beltramo, P. Girodet, Patrick Berger, Shuaib M Nasser, Stéphanie Fry, Sven P. Aries, Thomas Koehler, Timothy Harrison   +40 more
semanticscholar   +1 more source

BLOC1S1 Control of Vacuolar Organelle Fidelity Modulates Murine TH2 Cell Immunity and Allergy Susceptibility

Allergy, EarlyView.
Abbreviations: BLOC1S1, biogenesis of lysosome organelles complex 1 subunit 1; cGAS, cyclic GMP‐AMP synthase; GATA3, GATA binding protein 3; IgE, immunoglobulin E; IKK, inhibitor of nuclear factor kappa‐B kinase; IL, interleukin; mtDNA, mitochondrial DNA; NF‐κB, nuclear factor‐kappa B; OVA, ovalbumin; MC903, vitamin D3 analog; STING, stimulator of ...
Rahul Sharma, Kaiyuan Wu, Kim Han, Anna Chiara Russo, Pradeep K. Dagur, Christian A. Combs, Xianglan Yao, Stewart J. Levine, Michael N. Sack   +8 more
wiley   +1 more source

Severe Asthma or Chronic Obstructive Pulmonary Disease with Eosinophilic Inflammation? From Uncertainty to Remission under Anti IL-5R Therapy

Medicina
Background and Objectives: Severe adult-onset eosinophilic asthma and COPD with eosinophilic inflammation are two entities with a similar clinical course and are sometimes difficult to differentiate in clinical practice, especially in patients with a ...
Bianca Oprescu, Oana Raduna, Stefan Mihaicuta, Stefan Frent   +3 more
doaj   +1 more source

Inflammatory Airway Disease of Horses - Revised Consensus Statement [PDF]

, 2016
The purpose of this manuscript is to revise and update the previous consensus statement on inflammatory airway disease (IAD) in horses. Since 2007, a large number of scientific articles have been published on the topic and these new findings have led to ...
Cardwell, J M, Couetil, L L, Gerber, V, Lavoie, J P, Leguillette, R, Richard, E A   +5 more
core   +3 more sources

P69 An exploratory study to investigate the relationship between fraction of exhaled nitric oxide (FeNO) home monitoring and eosinophilic airway inflammation in adults with severe asthma [PDF]

, 2015
CR Nanda, Amisha Singapuri, Marcia Soares, Will Monteiro, Salman Siddiqui, Sherif Gonem   +5 more
openalex   +1 more source