Results 161 to 170 of about 1,917,601 (292)

Characteristics of Patients with Severe Uncontrolled Asthma in Saudi Arabia: A Cross-Sectional Study

Journal of Asthma and Allergy
Riyad O Al-Lehebi,1,2 Rana A Saleh,3 Abdalla M Alasiri,4 Bader J Alghamdi,5,6 Hajer Y Almudaiheem,7,8 Ahmed H Al-jedai,8,9 Eid A Almutairi,3 Haifa Aldakhil,10 Khaulah A Alokili,7 Fahad Zuriqan,7 Adeeb A Bulkhi11 1Pulmonary Department, King Fahad Medical ...
Al-Lehebi RO, Saleh RA, Alasiri AM, Alghamdi BJ, Almudaiheem HY, Al-jedai AH, Almutairi EA, Aldakhil H, Alokili KA, Zuriqan F, Bulkhi AA   +10 more
doaj  

Selective Absence of Co‐Inhibitory Receptor‐Expressing CD4+ T Cells in Lungs of Obese House Dust Mite‐Allergic C57BL/6 Mice

Allergy, EarlyView.
Obesity altered the inflammatory phenotype of HDM‐induced allergic airway inflammation in C57BL/6 mice, indicated by changed BAL cell composition. Single‐cell CITE‐Seq identified the lack of a CD4+ T‐cell subcluster characterized by co‐inhibitory receptor expression in obese HDM‐exposed C57BL/6 mice.
Sarah Miethe, Daniel P. Potaczek, Kim Pauck, Andrea Berlin, Bilal Alashkar Alhamwe, Stefanie Hagner, Andrea Nist, Elke Pogge von Strandmann, Thorsten Stiewe, Paul Klemm, Hartmann Raifer, Clemens Thölken, Holger Garn   +12 more
wiley   +1 more source

Impact of IL-5 Pathway Inhibition on Circulating Eosinophil- and Remodeling-Related Biomarkers in Severe Eosinophilic Asthma. [PDF]

J Asthma Allergy
Damiański P, Kumor-Kisielewska A, Białas AJ, Kuna P, Kupczyk M.   +4 more
europepmc   +1 more source

Asthma Remission From Childhood to Young Adulthood–A Population‐Based Cohort Study

Allergy, EarlyView.
Among 257 participants with asthma at age 8 years, 39% achieved symptom‐based remission by age 24, 29% achieved clinical remission, and 18% achieved complete remission. Male sex increased the likelihood of symptom‐based remission, while food sensitization and overweight/obesity decreased the likelihood.
Lina Broström, Anna Bergström, Anne‐Sophie Merritt, Maria Ödling, Erik Melén, Inger Kull, Sandra Ekström   +6 more
wiley   +1 more source

Clinical remission and associated factors in severe eosinophilic asthma patients treated with benralizumab: a real-world study. [PDF]

BMC Pulm Med
Yağdıran M, Aksu K.
europepmc   +1 more source

Effectiveness of mepolizumab on mucus plugs and clinical outcomes in severe eosinophilic asthma with and without coexisting bronchiectasis: a prospective pilot study. [PDF]

ERJ Open Res
Campisi R, Nolasco S, Mancuso M, Nardo AA, Intravaia R, Pelaia C, Vancheri C, Crimi N, Crimi C.   +8 more
europepmc   +1 more source

Decoding the “Metallic” Immune Imprint: Single‐Cell Exposomics Reveals the Immune Imprint of Fire Smoke

Allergy, EarlyView.
Takafumi Kubota, Yuki Matsumoto, Takahiro Tabuchi   +2 more
wiley   +1 more source

Rademikibart for Asthma With Type 2 Biomarkers: Exploratory Subgroup Analyses From a Phase 2b Randomized Clinical Trial

Allergy, EarlyView.
This study reports exploratory and predominantly post hoc subgroup analyses, according to baseline eosinophil count and FeNO levels. In adults with moderate‐to‐severe uncontrolled asthma, rademikibart produced rapid and sustained improvements in lung function and asthma control.
Michael E. Wechsler, Praveen Akuthota, Barry Quart, Raúl Collazo   +3 more
wiley   +1 more source

Clinical Remission in Patients with Severe Eosinophilic Asthma - A Single-Arm Observational Study with Benralizumab. [PDF]

J Asthma Allergy
Pavlov N, Bridevaux PO, Jandus P, Charbonnier F, Schuoler C, Wörner PM, Leuppi JD, Rothe T, Stolz D.   +8 more
europepmc   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source