Results 281 to 290 of about 93,898 (384)

Prognostic Factors in Severe Eosinophilic Asthma in a Pediatric Population: A Prospective Cohort Study in Spain. [PDF]

J Clin Med
Padró-Casas C, Basagaña M, Martínez-Colls MDM, García-Olivé I, Pollan Guisasola C, Teniente-Serra A, Martínez-Cáceres E, Navarro JT, Martínez-Rivera C.   +8 more
europepmc   +1 more source

Clinical Remission Outcome in Chinese Patients With Severe Asthma With an Eosinophilic Phenotype Receiving Mepolizumab: A Post-hoc Analysis of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial [PDF]

Ruchong Chen, Yuanrong Dai, Danrong Yang, Chuntao Liu, Wei Han, Wei Gu, Jie Cao, Qiong Zhou, Peter Howarth, Stephen Weng, Cui Xiong, Jie Huang, Peiwen Liang, Nanshan Zhong, on behalf of the 201536 Study Group   +14 more
openalex   +1 more source

Monocyte Chemotactic Factors in the Airways of Patients With Mild Asthma Before and After an Allergen Challenge

Allergy, EarlyView.
Nami Shrestha Palikhe, Yingqi Wu, Karen J. Howie, Caitlin Stevens, Jennifer Mitchell, Lesley Wiltshire, Gail M. Gauvreau, Harissios Vliagoftis   +7 more
wiley   +1 more source

Oesophageal Epithelial Cell‐Intrinsic MHCII Regulates Food Antigen‐Dependent Eosinophilic Esophagitis in an IFNγ‐Dependent Manner

Clinical &Experimental Allergy, EarlyView.
We found that oesophageal epithelial cells upregulate MHCII expression during active EoE in humans and a mouse model. MHCII expression by EECs was governed by IFNγ‐inducible transcriptional elements. EEC‐intrinsic MHCII promoted regulatory T cell accumulation and attenuated eosinophilic oesophageal inflammation.
Eric M. Rodríguez‐López, Rachel L. Clement, Megha Lal, Yusen Zhou, Stephen D. Carro, Charles‐Antoine Assenmacher, Ravi Gautam, Jarad Beers, Amanda B. Muir, Jonathan M. Spergel, Melanie A. Ruffner, Laurence C. Eisenlohr, David A. Hill   +12 more
wiley   +1 more source

Efficacy and safety of benralizumab in elderly patients with severe eosinophilic asthma. [PDF]

Eur Clin Respir J
Somekawa K, Watanabe K, Seki K, Muraoka S, Izawa A, Kaneko A, Otsu Y, Hirata M, Kubo S, Tanaka K, Nagasawa R, Matsumoto H, Murohashi K, Fuji H, Aoki A, Horita N, Hara Y, Kobayashi N, Kudo M, Kaneko T.   +19 more
europepmc   +1 more source

Markedly Increased Diamine Oxidase During Acute Anaphylaxis Is Associated With an Underlying Clonal Mast Cell Disorder

Clinical &Experimental Allergy, EarlyView.
We provide the first evidence that pronounced release of DAO during anaphylaxis is restricted to patients with clonal mast cell disorder. This finding offers possible functional support for the reported association between KIT p.D816V and anaphylaxis severity.
Matija Rijavec, Žan Kogovšek, Jezerka Inkret, Peter Kopač, Mitja Košnik, Peter Korošec   +5 more
wiley   +1 more source

Modifiable Risk Factors for Symptom Burden in Chronic Rhinosinusitis With Nasal Polyps: The Role of Obesity and Sleep Apnoea

Clinical Otolaryngology, EarlyView.
ABSTRACT Objective To identify sociodemographic and clinical predictors of symptom severity and quality of life (QoL) impairment in patients with chronic rhinosinusitis with nasal polyps (CRSwNP), diagnosed according to the latest EPOS 2020 criteria. Study Design Cross‐sectional analytical study.
Javier Modesto García‐Fernández, María Soledad Sánchez‐Torices, María Pilar Gómez‐Gallego, Miguel Ángel Feliz‐Fernández, María Alharilla Montilla‐Ibáñez, Rafael Lomas‐Vega   +5 more
wiley   +1 more source

The economic burden of asthma in Italy: evaluating the potential impact of different treatments in adult patients with severe eosinophilic asthma. [PDF]

Eur J Health Econ
Scortichini M, Mennini FS, Marcellusi A, Paoletti M, Tomino C, Sciattella P.   +5 more
europepmc   +1 more source

Endoscopically assessed mucus parameters in equine asthma: Relationship to clinical history and cytological findings data

Equine Veterinary Journal, EarlyView.
Abstract Background Mucus parameters are hallmark diagnostic features of equine asthma (EA). Objectives To investigate the relationship between mucus quantity score and mucus viscosity score with signalment, history, clinical findings and cytological parameters. Study Design Retrospective cross‐sectional study.
Julia Drespling, Leonie Berwanger, Heike Kühn, Bianca Schwarz, Marcus Doherr, Lars Mundhenk   +5 more
wiley   +1 more source