Results 261 to 270 of about 1,917,601 (292)

Reslizumab in the Treatment of Severe Eosinophilic Asthma: an Update

Immunotherapy, 2018
A marked heterogeneity is exhibited by asthma both clinically and at the molecular level with different phenotypes driven by diverse mechanistic pathways that require specifically targeted treatments. Biologics aimed at IL-4/13, IL-5 or IgE are proven or potentially effective treatments for patients with difficult to treat eosinophilic asthma ...
openaire   +2 more sources

The prevalence of severe asthma and severe eosinophilic asthma in Finland

Epidemiology, 2023
Arja Viinanen, Pinja Ilmarinen, Juha Mehtälä, Tero Ylisaukko-Oja, Juhana J Idänpään-Heikkilä, Hannu Kankaanranta, Lauri Lehtimäki   +6 more
openaire   +1 more source

Biological treatment is approved for severe eosinophilic asthma

BMJ, 2016
Draft guidance from the National Institute for Health and Care Excellence (NICE) recommends the monoclonal antibody mepolizumab as an option to treat adult patients with severe refractory asthma and raised eosinophil levels.1 The decision follows an agreement by the manufacturer, GlaxoSmithKline (GSK), to reduce the price of the drug—which has a list ...
openaire   +2 more sources

Primary lysis of eosinophils in severe desquamative asthma

Clinical & Experimental Allergy, 2014
SummaryPrimary lysis of eosinophils liberates free eosinophil granules (FEGs) releasing toxic proteins in association with bronchial epithelial injury repair. Eosinophil lysis may be significantly pathogenic. Bronchial mucosal FEGs are associated with uncontrolled asthma, severe asthma, aspirin‐sensitive asthma, and lethal asthma. FEGs in the bronchial
openaire   +2 more sources

Eosinophilic and noneosinophilic asthma: Beyond severe asthma

2023
Tara F. Carr, Sanjay B. Patel
openaire   +1 more source

Emerging Therapies in Severe Eosinophilic Asthma

Archivos de Bronconeumología (English Edition), 2017
Pee Hwee, Pang, Christopher E, Brightling   +1 more
openaire   +2 more sources

Severe Eosinophilic Asthma

2021
openaire   +1 more source

Real-World Effectiveness of Benralizumab in Severe Eosinophilic Asthma

Chest, 2021
Brian D Kent, David J Jackson, Abdel Douiri   +2 more
exaly  

Severe eosinophilic asthma and mepolizumab

The Lancet Respiratory Medicine, 2016
openaire   +2 more sources

Efficacy and Safety of Mepolizumab in a Real-World Cohort of Patients With Severe Eosinophilic Asthma

Journal of Asthma, 2021
Barak Pertzov, Dorit Shitenberg, Osnat Shtraichman   +2 more
exaly