Results 291 to 300 of about 327,068 (394)

Staphylococcus aureus Enterotoxin-Specific IgE Sensitization in Severe Eosinophilic Asthma Phenotype. [PDF]

Allergy Asthma Immunol Res, 2023
Chung KF.
europepmc   +1 more source

Switching Treatment from Mepolizumab to Benralizumab for Elderly Patients with Severe Eosinophilic Asthma: A Retrospective Observational Study

, 2022
Shoko Isoyama, Nobuhisa Ishikawa, Kosuke Hamai, Mirai Matsumura, Hiroki Kobayashi, Akio Nomura, Sayaka Ueno, Takuya Tanimoto, Hiroyuki Maeda, Hiroshi Iwamoto, Noboru Hattori   +10 more
openalex   +2 more sources

Persistent Eosinophilic Inflammation Is Not a Feature of Type 2 CRS Patients Failing Anti‐IL‐5R Therapy and Requiring Class Switching to Anti‐IL‐4/13

International Forum of Allergy &Rhinology, Volume 15, Issue 6, Page 602-607, June 2025.
ABSTRACT Background Type 2 inflammation dominates eosinophilic chronic rhinosinusitis (eCRS) and adult onset asthma. IL‐4, ‐5, and ‐13 are prominent disease mediators. Disease control can be achieved with biologic therapies. However, despite some patients entering remission, others experience poor control. Aim We aimed to describe eCRS patients treated
Peta‐Lee Sacks, Christian M Meerwein, Peter Earls, Cedric Thiel, Christine Choy, Raewyn G Campbell, Raymond Sacks, Larry Kalish, Richard J Harvey   +8 more
wiley   +1 more source

Early and Sustained Response to Benralizumab in Severe, Eosinophilic Asthma: A Real-World Observational Study. [PDF]

J Asthma Allergy
Stolz D, Schuoler C, Charbonnier F, Bridevaux PO, Jandus P, Leuppi JD, Pavlov N, Piecyk A, Rothe T.   +8 more
europepmc   +1 more source

A Case Study Showing Benralizumab’s Effectiveness in Treating Uncontrolled Severe Eosinophilic Asthma that is Resistant to Omalizumab

, 2022
Stelphy Stephen
openalex   +1 more source

Type 2 gene expression signature in severe asthma associates with more advanced airway remodeling

Clinical and Translational Allergy, Volume 15, Issue 6, June 2025.
Abstract Background Asthma is a heterogeneous disease with various inflammatory subtypes, including the type‐2 (T2) endotype associated with airway eosinophilia. Severe asthma is linked to reduced ventilatory function due to airway structural changes.
Bogdan Jakiela, Karolina Górka, Iwona Gross‐Sondej, Sławomir Mikrut, Krzysztof Okoń, Piotr Sadowski, Anna Andrychiewicz, Hanna Plutecka, Tomasz Stachura, Grażyna Bochenek, Stanisława Bazan‐Socha, Krzysztof Sładek, Jerzy Soja   +12 more
wiley   +1 more source

Global Burden of Asthma, and Its Impact on Specific Subgroups: Nasal Polyps, Allergic Rhinitis, Severe Asthma, Eosinophilic Asthma

, 2023
Adrian Paul J. Rabe, Wei Jie Loke, Khushboo Gurjar, Allison Brackley, Don Eliseo Lucero‐Prisno   +4 more
openalex   +2 more sources

Bifidobacterium animalis subsp. lactis A6 alleviates perennial allergic rhinitis in adults by inhibiting serum total IgE and IL‐13: A randomized, double‐blind, placebo‐controlled trial

Clinical and Translational Allergy, Volume 15, Issue 6, June 2025.
Abstract Objectives The evidence regarding the efficacy of probiotics in improving allergic rhinitis (AR) remains inconsistent. This study aimed to evaluate the potential effects of Bifidobacterium animalis subsp. lactis A6 (A6) on perennial AR.
Langrun Wang, Shiwen Zhou, Huiyu Chen, Chao Zhang, Meiwen Sun, Qi Zhang, Yinghua Liu, Shaoqi Shi, Shaoyang Ge, Juan Chen, Yanling Hao, Yong Zhang, Bing Fang, Jingjing He, Ran Wang   +14 more
wiley   +1 more source

Prognostic Factors in Severe Eosinophilic Asthma in a Pediatric Population: A Prospective Cohort Study in Spain. [PDF]

J Clin Med
Padró-Casas C, Basagaña M, Martínez-Colls MDM, García-Olivé I, Pollan Guisasola C, Teniente-Serra A, Martínez-Cáceres E, Navarro JT, Martínez-Rivera C.   +8 more
europepmc   +1 more source

Using the 6-min walk test to assess the clinical response to mepolizumab and conventional therapy in severe eosinophilic asthma. [PDF]

ERJ Open Res, 2023
Lombardi C, Berti A, Cottini M, Roca E, Ventura L.   +4 more
europepmc   +1 more source