Results 291 to 300 of about 93,898 (384)

Clinical characterisation of exacerbations of severe eosinophilic asthma occurring on mepolizumab and placebo. [PDF]

ERJ Open Res
Howell I, Bratton DJ, Hynes G, Yancey SW, Heaney LG, Pavord ID, Shrimanker R.   +6 more
europepmc   +1 more source

Relationship Between Bronchodilator Reversibility and Spirometry Response to Dupilumab in Type 2 High Uncontrolled Severe Asthma

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 253-255, March 2025.
Robert Greig, Kirsten Stewart, Chris RuiWen Kuo, Rory Chan, Brian Lipworth   +4 more
wiley   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Long-Term Eosinophil Depletion: A Real-World Perspective on the Safety and Durability of Benralizumab Treatment in Severe Eosinophilic Asthma. [PDF]

J Clin Med
Menzella F, Marchi M, Caminati M, Romagnoli M, Micheletto C, Bonato M, Idotta G, Nizzetto M, D'Alba G, Cavenaghi M, Bortoli M, Beghè B, Pini L, Benoni R, Casoni G, Muzzolon R, Michieletto L, Bosi A, Mastrototaro A, Diamandi A, Nalin M, Senna G.   +21 more
europepmc   +1 more source

Evaluation of Small Airways Dysfunction With Dupilumab Using Airway Oscillometry in Uncontrolled Severe Asthma

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 264-266, March 2025.
Kirsten E. Stewart, Chris RuiWen Kuo, Rory Chan, Brian J. Lipworth   +3 more
wiley   +1 more source

Genetic Determinants of Peanut‐Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP Study

Immunology, EarlyView.
A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanika Kanchan, Karen Cerosaletti, James A. Perry, George DuToit, Monali Manohar, Hua Ling, Justin E. Paschall, Srinath Sanda, R. Sharon Chinthrajah, Gerald T. Nepom, Kari C. Nadeau, Stacie M. Jones, Gideon Lack, Ingo Ruczinski, Rasika A. Mathias   +14 more
wiley   +1 more source

Case Report: Dual monoclonal antibody therapy in chronic rhinosinusitis with nasal polyps and severe eosinophilic asthma-a proteome analysis. [PDF]

Front Allergy
Blauwblomme M, Gevaert P, Van Nevel S, Riemann S, Vandewalle E, Holtappels G, De Ruyck N, Derycke L, Eeckels AS, Vanhee S, Lambrecht BN, Brusselle G, Van Zele T.   +12 more
europepmc   +1 more source

Unsupervised Machine Learning Identifies Asthma Phenotypes in the Population‐Based West Sweden Asthma Study

Clinical &Experimental Allergy, EarlyView.
Muwada Bashir Awad Bashir, Daniil Lisik, Saliha Selin Ozuygur Ermis, Rani Basna, Reshed Abohalaka, Selin Ercan, Helena Backman, Teet Pullerits, Roxana Mincheva, Göran Wennergren, Madeleine Rådinger, Jan Lötvall, Linda Ekerljung, Hannu Kankaanranta, Bright I. Nwaru   +14 more
wiley   +1 more source

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta, Tong Wang, Susmita, Ditte Marie L. Saunte, Roderick Hay, Vincent Piguet   +5 more
wiley   +1 more source

Effects of benralizumab in patients with severe eosinophilic asthma (SEA): A plain language summary of the ANANKE study. [PDF]

Immunotherapy
Canonica GW, Consani L, Malerba L, Pelaia G, Vultaggio A, ANANKE investigators.   +5 more
europepmc   +1 more source