Results 301 to 310 of about 93,898 (384)

Therapeutic advances in pruritus as a model of personalized medicine

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Recent advances in itch biology reveal that chronic pruritus arises from distinct neuroimmune pathways driven by cytokines, JAK, BTK and GPCRs. Targeted biologics and small molecule inhibitors such as dupilumab, nemolizumab, remibrutinib and JAK inhibitors precisely modulate these pathways, leading to a new era of personalized therapeutics in pruritus.
Kelsey Auyeung, Ramsey Kubofcik, Brian S. Kim   +2 more
wiley   +1 more source

Benralizumab in severe eosinophilic asthma by biologic use and key clinical subgroups: real-world XALOC-1 programme: a plain language summary of publication. [PDF]

Immunotherapy
Jackson DJ, Pelaia G, Emmanuel B, Tran TN, Cohen D, Shih VH, Shavit A, Arbetter D, Katial R, Rabe APJ, Garcia Gil E, Pardal M, Nuevo J, Watt M, Boarino S, Kayaniyil S, Loureiro CC, Padilla-Galo A.   +17 more
europepmc   +1 more source

Bacterial biogeography of adult airways in atopic asthma [PDF]

, 2018
Beigelman, Avraham, Castro, Mario, et al,   +2 more
core   +1 more source

Overlapping forms of granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis: Insights from a European multicenter study

Journal of Internal Medicine, EarlyView.
Abstract Background Granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis (EGPA) are distinct forms of antineutrophil cytoplasm antibody (ANCA)‐associated vasculitis (AAV). Increasing evidence suggests overlapping features, particularly in proteinase 3 (PR3)‐ANCA‐positive EGPA and GPA with eosinophilia.
Federica Pallotti, Camille Mettler, Matthias Papo, Michele Iudici, Roberto Padoan, Boris Sorin, Francesca Regola, Franco Franceschini, Sergey Moiseev, Pavel Novikov, Mario Andrea Piga, Gianluca Moroncini, Silke R. Brix, Abdul Hadi Kafagi, Samuel Deshayes, Achille Aouba, Julien Campagne, Paolo Delvino, Jan Willem Cohen Tervaert, Luisa Brussino, Martin Michaud, Nils Venhoff, Federico Alberici, Claudia Iannone, Sophie Rosenstingl, Marin Moutel, Jean‐Marc Galempoix, Vincent Cottin, Clara Jaccard, Diane Riehl, Paul Legendre, Anne Claire Billet, Paola Parronchi, Luca Quartuccio, Vitor Teixeira, Allyson Egan, David Jayne, Enrico Tombetti, Marco Caminati, Christian Pagnoux, Alexis Regent, Marc Ruivard, Loïc Guillevin, Xavier Puéchal, Benjamin Terrier, the French Vasculitis Study Group (FVSG)   +45 more
wiley   +1 more source

SingleNucleotide Polymorphisms as Biomarkers of Mepolizumab and Benralizumab Treatment Response in Severe Eosinophilic Asthma. [PDF]

Int J Mol Sci
Rojo-Tolosa S, Sánchez-Martínez JA, Caballero-Vázquez A, Pineda-Lancheros LE, González-Gutiérrez MV, Pérez-Ramírez C, Jiménez-Morales A, Morales-García C.   +7 more
europepmc   +1 more source

The Milan Score is an Effective Manometric Tool to Predict Gastroesophageal Reflux in Patients With Laryngopharyngeal Symptoms

Neurogastroenterology &Motility, EarlyView.
Patients with isolated LPS demonstrated a lower likelihood of EGJ disruption, pathologic GERD, and abnormal Milan score. The Milan score performed similarly well in the identification of GERD in both LPS and typical symptoms. The Milan score could therefore be used as an upfront test in LPS patients.
Stefano Siboni, Marco Sozzi, Pierfrancesco Visaggi, Ivan Kristo, Nicola De Bortoli, Salvatore Tolone, Elisa Marabotto, Daniele Bernardi, Sebastian F. Schoppmann, Roberto Penagini, Benjamin Rogers, Anthony Hobson, Jordan Haworth, Brian Louie, Yeong Yeh Lee, Vincent Tee, Takahiro Masuda, Dimitrios Theodorou, Tania Triantafyllou, Benedetta Barcella, Lorenzo Cusmai, Michele Puricelli, Marina Coletta, Vito Annese, Edoardo Vincenzo Savarino, Emanuele Luigi Giuseppe Asti, C. Prakash Gyawali   +26 more
wiley   +1 more source

Durability of benralizumab effectiveness in severe eosinophilic asthma patients with and without chronic rhinosinusitis with nasal polyps: a <i>post hoc</i> analysis from the ANANKE study. [PDF]

Front Allergy
Brussino L, Aliani M, Altieri E, Bracciale P, Caiaffa MF, Cameli P, Canonica GW, Caruso C, Centanni S, De Michele F, Del Giacco S, Di Marco F, Malerba L, Menzella F, Pelaia G, Rogliani P, Romagnoli M, Schino P, Schroeder JW, Senna G, Vultaggio A, D'Amato M.   +21 more
europepmc   +1 more source

Isolated Mast Cell–Mediated Angioedema: Clinically Different but Endotypically Similar to Chronic Spontaneous Urticaria

Clinical &Experimental Allergy, EarlyView.
Thomas Buttgereit, Claudia Hayford, Carolina Vera Ayala, Sherezade Moñino‐Romero, Yi‐Kui Xiang, Pavel Kolkhir, Carolin Steinert, Denise Freier, Markus Magerl, Jörg Scheffel, Karsten Weller   +10 more
wiley   +1 more source

The effects of e‐cigarette use on asthma severity in adult BALB/c mice

Experimental Physiology, EarlyView.
Abstract Electronic cigarettes (e‐cigarettes) are often perceived to be a less harmful alternative to tobacco cigarettes. Potentially due to this perception, they are used by people with pre‐existing respiratory conditions, such as asthma, who otherwise would not smoke. Despite this, there are few studies exploring the health effects of e‐cigarette use
Jenield J. D'abreo, Emily K. Chivers, Peter B. Noble, Luke J. Berry, Rachel R. Huxley, Arthur (Bill) W. Musk, Peter J. Franklin, Benjamin J. Mullins, Katherine R. Landwehr, Alexander N. Larcombe   +9 more
wiley   +1 more source

Very long-term data on patients with severe eosinophilic asthma treated with mepolizumab: a case series. [PDF]

Drugs Context
Lombardi C, Menzella F, Berti A.
europepmc   +1 more source