Results 311 to 320 of about 87,993 (377)

Advancing Remission in Severe Asthma With Benralizumab: Latest Findings, Current Perspectives and Future Direction

open access: yesClinical &Experimental Allergy, Volume 55, Issue 7, Page 521-531, July 2025.
ABSTRACT The introduction of biologics, such as benralizumab (an anti‐IL‐5 receptor α humanised monoclonal antibody), has made remission a feasible goal for patients with severe eosinophilic asthma (SEA). However, there are remaining research gaps and no clear consensus on the definition of remission.
Renaud Louis   +7 more
wiley   +1 more source

Study on the Combined Effects and Mechanisms of Acupoint Catgut Embedding in Improving Sleep Quality and Controlling Asthma Symptoms in Patients With Asthma

open access: yesThe Clinical Respiratory Journal, Volume 19, Issue 7, July 2025.
The analysis of the effects of acupoint catgut embedding therapy on asthma control, sleep quality, as well as immune and inflammatory factors. Univariate and multivariate analysis of the effects of acupoint catgut embedding therapy. ABSTRACT Background Asthma is a chronic airway inflammatory disease that significantly affects patients' quality of life ...
Zhihong Shi   +6 more
wiley   +1 more source

Impact of biological therapies on laboratory outcomes and FEV1 in patients with severe eosinophilic asthma with chronic rhinosinusitis: a real-life study from Saudi Arabia. [PDF]

open access: yesMultidiscip Respir Med
Abu Elhassan U   +16 more
europepmc   +1 more source

Evaluation of the Effects of Switching COPD Patients From LAMA/LABA Therapy to ICS/LAMA/LABA Therapy Using the Impulse Oscillation System (IOS) Capable of Separating Inspiratory and Expiratory Measurements

open access: yesThe Clinical Respiratory Journal, Volume 19, Issue 7, July 2025.
This study assessed the effect of switching from dual bronchodilator therapy to triple therapy in COPD. While FEV1 showed no significant change, resonant frequency improved, suggesting reduced airway inflammation. Impulse oscillometry may help detect treatment effects not captured by spirometry.
Yosuke Tanaka   +11 more
wiley   +1 more source

Sustained Effectiveness of Benralizumab in Naïve and Biologics-Experienced Severe Eosinophilic Asthma Patients: Results from the ANANKE Study. [PDF]

open access: yesJ Asthma Allergy
Cameli P   +22 more
europepmc   +1 more source

Gluten‐related skin disorders: clinical presentation, diagnostic and treatments

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 7, Page 857-867, July 2025.
Summary Gluten‐related disorders (GRDs) encompass a spectrum of clinical manifestations triggered by gluten ingestion in genetically susceptible individuals. These disorders include celiac disease (CD) and non‐celiac gluten sensitivity (NCGS) and present with both intestinal and extraintestinal symptoms, including skin manifestations.
Dario Didona   +2 more
wiley   +1 more source

ILC2 Diversity, Location, and Function in Pulmonary Disease

open access: yesImmunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma   +2 more
wiley   +1 more source

Pathological IgE Production in Inborn Errors of Immunity and Beyond

open access: yesImmunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT In this review, we examine different mechanisms for the generation of pathological IgE through the study of inborn errors of immunity (IEI). In particular, we focus on IEIs that are susceptible to atopic disease, such as severe eczema, eosinophilia, and/or food anaphylaxis; this group of approximately 50 genes has been coined primary atopic ...
Cindy S. Ma, Peter S. Hsu
wiley   +1 more source

Dad's legacy: Epigenetic reprogramming and paternal inflammatory memory in offspring health

open access: yesJournal of Internal Medicine, Volume 298, Issue 1, Page 16-30, July 2025.
Abstract Over the past decade, numerous reports have highlighted intergenerational and even transgenerational epigenetic effects resulting from parental exposure to diets, toxins, and stress. In many cases, these parentally induced phenotypes do not seem to confer an obvious benefit, making it challenging to understand the evolutionary drivers behind ...
Shamila D. Alipoor   +3 more
wiley   +1 more source

Real-world outcomes of mepolizumab for the treatment of severe eosinophilic asthma in Canada: an observational study. [PDF]

open access: yesAllergy Asthma Clin Immunol
Chapman KR   +7 more
europepmc   +1 more source

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