ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of small‐vessel vasculitis typically associated with eosinophilia, asthma, and systemic inflammation. Although peripheral neuropathies are relatively common, central nervous system involvement, especially intracerebral hemorrhage during the remission phase of EGPA, is uncommon,
Shinya Watanabe +2 more
wiley +1 more source
Sinonasal Outcomes Obtained after 2 Years of Treatment with Benralizumab in Patients with Severe Eosinophilic Asthma and CRSwNP: A "Real-Life" Observational Study. [PDF]
De Corso E +20 more
europepmc +1 more source
ABSTRACT Primary diffuse type 2‐dominant chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory disease of the nasal cavity and paranasal sinuses associated with significant morbidity. Impaired sense of smell is a cardinal symptom of CRSwNP and one of the most burdensome for patients, impacting quality of life, mental health, and even ...
Thomas S. Higgins +9 more
wiley +1 more source
Chronic Rhinosinusitis and Autoimmune Diseases: A Comprehensive Large Population‐Based Analysis
ABSTRACT Objectives To evaluate associations between a wide variety of autoimmune diseases and chronic rhinosinusitis without nasal polyposis (CRSsNP), CRS with nasal polyposis (CRSwNP), and the need for endoscopic sinus surgery. Methods This is a multicenter retrospective study from January 1, 2010 to July 31, 2025 utilizing data from 106 healthcare ...
Robert E. Africa +3 more
wiley +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Long-term effects of mepolizumab in patients with severe eosinophilic asthma: a 6-year real-life experience. [PDF]
Stanziola AA +6 more
europepmc +1 more source
Benralizumab: Effectiveness in Patients with Uncontrolled Severe Eosinophilic Asthma at 6 and 12 Months at a Third-Level Care Hospital. Capacity for ICS-LABA Therapy Reduction. [PDF]
González-Tuyub YH +3 more
europepmc +1 more source
Imaging findings and clinical outcome in three cats with possible inflammatory ureteritis
Abstract Three adult cats presented to our institution for evaluation of non‐specific clinical signs and azotaemia. All cats had sonographic evidence of renal pelvic and ureteral dilation, concerning for a ureteral obstruction without a definitive mechanical cause identified. Anti‐inflammatory doses of corticosteroids were administered over an extended
Elisa L. Heacock +3 more
wiley +1 more source
Sustained Effectiveness of Benralizumab in Naïve and Biologics-Experienced Severe Eosinophilic Asthma Patients: Results from the ANANKE Study. [PDF]
Cameli P +22 more
europepmc +1 more source
Impact of biological therapies on laboratory outcomes and FEV1 in patients with severe eosinophilic asthma with chronic rhinosinusitis: a real-life study from Saudi Arabia. [PDF]
Abu Elhassan U +16 more
europepmc +1 more source

