Results 71 to 80 of about 27,014 (195)

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Additional file 2 of Proteomics-based diagnostic peptide discovery for severe fever with thrombocytopenia syndrome virus in patients [PDF]

, 2022
Additional file 2: Figure S1. MS/MS spectra of tryptic peptides derived from the N protein in serum samples from patients infected with severe fever with thrombocytopenia syndrome virus (SFTSV).
Hayoung Lee (4854997), Chang-Seop Lee (4854994), Seung Il Kim (135677), Dongseob Tark (688803), Ju Yeon Lee (1471039), Giwan Seo (8734623), Nam Hoon Kim (812590), Edmond Changkyun Park (1743529), Hye-Yeon Kim (480560), Sangmi Jun (2526919), Sang-Yeop Lee (532177), Sung Ho Yun (532176)   +11 more
core   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source

Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome [PDF]

Journal of Clinical and Diagnostic Research, 2017
Hantaan Virus (HTNV) infections are mostly associated with fever, haemorrhagic and renal manifestations, known as Haemorrhagic Fever with Renal Syndrome (HFRS). We herein describe three cases with acute HTNV infection, confirming that HTNV infection may
Xiaopeng Yang, Sanming Chai, Xining Xu, Ling Hui, Meiliang Wang   +4 more
doaj   +1 more source

Low Serum Alkaline Phosphatase Levels in Paediatric sepsis Correlate With Acute Kidney Injury: A Multicenter Retrospective Study

Acta Paediatrica, EarlyView.
ABSTRACT Aims To investigate the association between serum ALP levels and the development of AKI in paediatric patients with sepsis. Methods Retrospective screening of a computerized database of 4 Israeli regional hospitals for children (0–18 years) hospitalized between 1.01.2000–1.06.2024 with ICD‐9 sepsis‐related diagnoses (study group) and age‐ and ...
Evgenia Gurevich, Ido Levi, Yehonatan Marziano, Michael Kalinin, Natalya Bilenko, Daniel Landau   +5 more
wiley   +1 more source

Roles of raccoons in the transmission cycle of severe fever with thrombocytopenia syndrome virus

Journal of Veterinary Medical Science, 2022
The present study investigated severe fever with thrombocytopenia syndrome virus (SFTSV) infection in raccoons in Wakayama Prefecture from 2007 to 2019. To perform surveillance, an enzyme-linked immunosorbent assay (ELISA) was established, and the sensitivity and specificity of the ELISA were 100% in comparison with a 50% focus-reduction neutralization
TATEMOTO, Kango, ISHIJIMA, Keita, KURODA, Yudai, MENDOZA, Milagros Virhuez, INOUE, Yusuke, PARK, Eunsil, SHIMODA, Hiroshi, SATO, Yuko, SUZUKI, Tadaki, SUZUKI, Kazuo, MORIKAWA, Shigeru, MAEDA, Ken   +11 more
openaire   +2 more sources

Diagnosis and management of neutropenia in adults: Expert guidance

British Journal of Haematology, EarlyView.
Severe neutropenia can result from decreased production of neutrophil precursors in the bone marrow, as in the case of severe congenital neutropenia, or from increased utilization of neutrophils or their accelerated destruction as for drug‐induced neutropenia or autoimmune neutropenia. Severe chronic neutropenia increases susceptibility to bacterial or
Karl Welte, Cornelia Zeidler, Julia Skokowa, Sabine Mellor‐Heineke, Audrey Anna Bolyard, David Dale   +5 more
wiley   +1 more source

Antiviral activity of lipoxygenase against severe fever with thrombocytopenia syndrome virus. [PDF]

Protein Cell
Li S, Zheng X, Zhang Y, Zhang L, Yang T, Li H, Zhou C, Zhang XA, Gao LZ, Liu W.   +9 more
europepmc   +3 more sources

Acute anaphylactic and multiorgan inflammatory effects of Comirnaty in pigs: evidence of spike protein mRNA transfection and paralleling inflammatory cytokine upregulation

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Rare but severe adverse events (AEs) associated with mRNA‐lipid nanoparticle (LNP) COVID‐19 vaccines, such as Comirnaty, include anaphylaxis and inflammatory organ disorders, but their underlying mechanisms are poorly understood. We aimed to develop an animal model to study these phenomena.
László Dézsi, Gábor Kökény, Gábor Szénási, Csaba Révész, Tamás Mészáros, Bálint A. Barta, Réka Facsko, Anna Szilasi, Tamás Bakos, Gergely T. Kozma, Attila B. Dobos, Béla Merkely, Tamás Radovits, János Szebeni   +13 more
wiley   +1 more source

18F-FDG PET and histopathologic findings in a patient with severe fever with thrombocytopenia syndrome [PDF]

, 2018
We report on a patient with severe fever with thrombocytopenia syndrome who fully recovered. Imaging with 2-deoxy-2-fluoro-glucose positron emission tomography showed hypermetabolism in regional lymph nodes and the spleen.
Ki Hyun Kim, Chung, Junho, Koh, Jiwon, Kim, Ki Hyun, Chang Kyung Kang, Jeon, Yoon Kyung, Choi, Su Jin, Jiwon Koh, Nam-Joong Kim, Wan Beom Park, Junho Chung, Su Jin Choi, Yoon Kyung Jeon, Pyoeng Gyun Choe, Kang, Chang Kyung, Kim, Nam-Joong, Park, Wan Beom, Myoung-don Oh, Oh, Myoung Don, Choe, Pyoeng Gyun   +19 more
core   +1 more source