Results 121 to 130 of about 1,750,371 (298)

Severe maternal and neonatal morbidity or mortality in forceps versus cesarean birth in the second stage of labor: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Approximately one in four first‐time mothers reach the second stage of labor but cannot have a spontaneous vaginal birth, necessitating an intervention such as forceps to facilitate birth. Objective This study synthesizes evidence comparing severe maternal morbidity (SMM) and neonatal morbidity or mortality (SNMM) following forceps ...
Irina I. Oltean, Abirami Kirubarajan, Giulia M. Muraca   +2 more
wiley   +1 more source

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

iNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang, Rongyu Guo, Xiaojun Feng, Liqin Tang   +3 more
wiley   +1 more source

Protective Effects of Imeglimin Against Oxaliplatin‐Induced Peripheral Neurotoxicity: Evidence From In Vitro and In Vivo Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Oxaliplatin is a platinum‐based anticancer agent widely used for gastrointestinal malignancies; however, it is known to cause dose‐dependent peripheral neuropathy (OIPN), a characteristic adverse effect. OIPN results in a reduced quality of life and often necessitates dose reduction or discontinuation of oxaliplatin; however, effective ...
Yusuke Koura, Kano Kinjo, Keisuke Mine, Yusuke Mori, Mami Ueda, Risa Kaneko, Yuna Kamiya, Taiga Sonoda, Haruka Mimata, Shunsuke Fujita, Takehiro Kawashiri, Daisuke Kobayashi   +11 more
wiley   +1 more source

Phenotypic and Genotypic Analysis of Two Rare Cases of ‐‐SEA/‐α4.3 HbH Disease

Journal of Clinical Laboratory Analysis, EarlyView.
We report two unrelated adult patients with rare deletional HbH disease (genotype ‐‐SEA/‐α4.3). This novel 4.3 kb deletion covering the HBA1 gene is accompanied by X‐Y‐Z segment recombination, which was identified by CycloneSEQ long‐read nanopore sequencing.
Weijia Yang, Xiaoyan Huang, Li Zhang, Xiaoqin Yang, Yaya Guo, Qingping Kang, Min Dou, Guijun Huang   +7 more
wiley   +1 more source

Preventing severe hypoglycemia in adults with type 2 diabetes (PHT2): Design, delivery and evaluation framework for a randomized controlled trial

\ua9 2024 Elsevier Inc.Background: Severe hypoglycemia is a common and feared complication of medications used to lower blood glucose levels in individuals with diabetes. Psychoeducational interventions can prevent severe hypoglycemia in individuals with
Bashir A, Hansell L, Speight J, Madziwa L, Cotton M, Hunt H, Rogers K, Ralston JD, Karter AJ, Singh U, Ludman E, Hsu C, Tschernisch K, Ng J, Ehrlich K, Yarborough L, Shaw JAM, Burns-Hunt D, Sergei Tschernisch S, Anderson M, Sweeny A, Shortreed SM, Levy SM, Sevey B, Omura EM   +24 more
core   +3 more sources

Pancreas–Intestine Composite Transplantation for Simultaneous Loss of Pancreatic and Intestinal Function (With Video)

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Pancreas–intestine composite transplantation (PITx) is a therapeutic option for patients with irreversible loss of both pancreatic and intestinal function. We report a case of PITx in a 16‐year‐old male who developed fulminant Type 1 diabetes mellitus complicated by non‐occlusive mesenteric ischemia, resulting in extensive intestinal necrosis.
Kei Yamane, Takashi Ito, Takayuki Anazawa, Junji Fujikura, Makoto Okabe, Satoshi Ishida, Koki Kurahashi, Masaaki Hirata, Hiroshi Kawamoto, Hiroto Nishino, Asahi Sato, Tomoaki Yoh, Hidenobu Kojima, Shinya Okumura, Takahiro Nishio, Daisuke Ueda, Hirofumi Hirao, Yuki Masano, Shoichi Kageyama, Katsunori Sakamoto, Satoshi Ogiso, Kazuyuki Nagai, Yoichiro Uchida, Takamichi Ishii, Etsuro Hatano   +24 more
wiley   +1 more source

ACE inhibitor use is associated with hospitalization for severe hypoglycemia in patients with diabetes

, 1997
OBJECTIVE - To evaluate the association between the use of ACE inhibitors and hospital admission for severe hypoglycemia and to explore the effects of potential confounding variables on this relationship.
Boyle, Douglas I R, McMahon, Alex, Evans, Josie, Newton, Ray W., Jung, Roland T., MacDonald, Thomas M, Morris, Andrew D, Morris, Andrew D., Mcmahon, Alexander D., Macdonald, Thomas M., Evans, Josie M.M., Pearce, Hilary, Jung, Roland T, Boyle, Douglas I.R., Newton, Ray W   +14 more
core   +1 more source

Low‐value glucose monitoring in noncritically ill hospitalized patients

Journal of Hospital Medicine, EarlyView.
Abstract Background Inpatient routine point‐of‐care glucose (POC‐G) monitoring is common given association of persistent hyperglycemia with increase in morbidity and mortality. However, some patients receive frequent fingerstick testing without needing insulin to reach glycemic targets.
Niloofar Latifi, Nestoras Mathioudakis, Mohammed S. Abusamaan, Megan M. Tschudy, Jianqiao Ma, Sarah Olson, Terra M. M. Jouaneh, Angie Yang, Daniel J. Brotman   +8 more
wiley   +1 more source

Descriptions of health states associated with increasing severity and frequency of hypoglycemia: a patient-level perspective

Patient Preference and Adherence, 2013
Stewart B Harris,1 Kamlesh Khunti,2 Mona Landin-Olsson,3 Claus B Galbo-Jørgensen,4 Mette Bøgelund,4 Barrie Chubb,5 Jens Gundgaard,6 Marc Evans71Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; 2Diabetes ...
Harris SB, Khunti K, Landin-Olsson M, Galbo-Jørgensen CB, Bøgelund M, Chubb B, Gundgaard J, Evans M   +7 more
doaj  

The Epidemiology of Severe Hypoglycemia in Type 2 Diabetes [PDF]

, 2019
The purpose of this dissertation is to explore the epidemiology of severe hypoglycemia in type 2 diabetes by examining risk factors and health outcomes associated with severe hypoglycemia.
Lee, Alexandra Kathryn
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