Results 101 to 110 of about 1,750,371 (298)

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Risk Factors of Hypoglycemic Encephalopathy and Prolonged Hypoglycemia in Patients With Severe Hypoglycemia

Journal of Clinical Medicine Research, 2019
The aim of the study was to investigate risk factors of hypoglycemic encephalopathy (HE) in patients with severe hypoglycemia.We retrospectively enrolled patients with severe hypoglycemia who were transported to the emergency department in an ambulance.
Saikawa, Rika, Yamada, Hodaka, Suzuki, Daisuke, Amamoto, Misato, Matsumoto, Yuko, Funazaki, Shunsuke, Yoshida, Masashi, Toyoshima, Hideo, Hara, Kazuo   +8 more
openaire   +3 more sources

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

Effect of Hypoglycemia and Rebound Hyperglycemia on Proteomic Cardiovascular Risk Biomarkers

Biomedicines
Introduction: Hypoglycemia has been associated with cardiovascular events, and glucose variability has been suggested to be associated with increased cardiovascular risk.
Manjula Nandakumar, Thozhukat Sathyapalan, Stephen L. Atkin, Alexandra E. Butler   +3 more
doaj   +1 more source

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

Pancreatic α‐cell dysfunction associated with equine insulin dysregulation

Equine Veterinary Journal, EarlyView.
Abstract Background Insulin dysregulation (ID) in horses is characterised by insulin resistance and exaggerated insulin responses, yet the underlying endocrine mechanisms remain incompletely understood. In humans, α‐cell dysfunction characterised by exaggerated glucagon secretion contributes to metabolic disease; however, the role of pancreatic α‐cell ...
Sanna Lindåse, Emma Strage, Josefin Söder, Johan Bröjer   +3 more
wiley   +1 more source

Minimizing the risk of hypoglycemia in patients with type 2 diabetes mellitus

, 2010
Pamela KushnerUniversity of California, Irvine College of Medicine, California, USAAbstract: Hypoglycemia is a major barrier to achieving glycemic goals in patients with diabetes.
Kushner P, Pamela Kushner
core  

A case of retrovesical fibrosarcoma with severe hypoglycemia [PDF]

, 1992
We report a case of retrovesical fibrosarcoma with severe hypoglycemia. A 67-year-old man was admitted to our hospital with second recurrence of the retrovesical tumor with hypoglycemia.
大川, 順正, 青枝, 秀男, 小村, 隆洋, 松本, 美代, 澤田, 佳久, 稲垣, 武, 平野, 敦之, 柑本, 康夫   +7 more
core  

Nutraceutical Benefits of Anchomanes difformis Rhizome and Its Effects on Blood Glucose and Hepatorenal Function in Normoglycemic Rats

Food Chemistry International, EarlyView.
Scientific analysis of Anchomanes difformis roots confirms significant nutraceutical potential, containing high levels of carbohydrates, proteins, and essential minerals. Phytochemical screening revealed antioxidants such as phenols and flavonoids, and although the extracts effectively lowered plasma glucose, safety testing showed dose‐dependent risks.
Lawrence Folorunso Dada, Kingsley Omage, Marshall Arebojie Azeke   +2 more
wiley   +1 more source