Results 41 to 50 of about 60,872 (263)

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Severe Hypoglycemia Following Acute Aluminum Phosphide (Rice Tablet) Poisoning; A Case Report and Review of the Literature [PDF]

Acta Medica Iranica, 2012
Aluminum phosphide (AlP) as 3 g tablet is widely used in Iran to protect stored food grains from pests. Hyperglycemia following its ingestion has been already reported in the recent years but severe hypoglycemia is uncommon. Here, we report a 19 year old
Omid Mehrpour, Abbas Aghabiklooei, Mohammad Abdollahi, Surjit Singh   +3 more
doaj   +2 more sources

Sepsis‐associated hypoglycemia on admission is associated with increased mortality in intensive care unit patients

Acute Medicine & Surgery, 2022
Aim Hyperglycemia is a common response to acute illness, but it is not often seen in critical conditions. The frequency and cause of hypoglycemia in septic patients have not been well elucidated.
Yumi Mitsuyama, Kentaro Shimizu, Sho Komukai, Atsushi Hirayama, Ryosuke Takegawa, Takeshi Ebihara, Tetsuhisa Kitamura, Hiroshi Ogura, Takeshi Shimazu   +8 more
doaj   +1 more source

Current and future therapies to treat impaired awareness of hypoglycemia

Frontiers in Pharmacology, 2023
In order to achieve optimal glycemic control, intensive insulin regimes are needed for individuals with Type 1 Diabetes (T1D) and insulin-dependent Type 2 Diabetes (T2D).
Erica L. Macon, Micah H. Devore, Yu Kuei Lin, Megan B. Music, Mason Wooten, Colleen A. McMullen, Andrea M. Woodcox, Ashlee R. Marksbury, Zachary Beckner, Bansi V. Patel, Lily A. Schoeder, Ashley N. Iles, Simon J. Fisher   +12 more
doaj   +1 more source

Islet Transplantation for Hypoglycemia Unawareness/Severe Hypoglycemia: Caveat Emptor [PDF]

Diabetes Care, 2016
Current estimates are that 1.25 million Americans have type 1 diabetes (T1D) (1) caused by the gradual loss of nearly all pancreatic insulin-producing β-cells via a presumed T cell–mediated autoimmune process (2). Eventually, all with T1D display severely impaired endogenous insulin production (3) and are dependent upon injected insulin for survival ...
openaire   +2 more sources

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Brain Regulation of Cardiac Function during Hypoglycemia

Metabolites, 2023
Hypoglycemia occurs frequently in people with type 1 and type 2 diabetes. Hypoglycemia activates the counter-regulatory response. Besides peripheral glucose sensors located in the pancreas, mouth, gastrointestinal tract, portal vein, and carotid body ...
Matthew E. Chambers, Emily H. Nuibe, Candace M. Reno-Bernstein   +2 more
doaj   +1 more source

Severe Hypoglycemia and Hyperinsulinemia in Falciparum Malaria

New England Journal of Medicine, 1983
We studied the occurrence, clinical manifestations, and mechanism of hypoglycemia in patients with falciparum malaria in eastern Thailand. Hypoglycemia, which was often severe and recurrent, occurred in 17 patients, including 12 in a series of 151 patients with cerebral malaria. Thirty episodes were investigated.
White, N, Warrell, D, Chanthavanich, P, Looareesuwan, S, Warrell, M, Krishna, S, Williamson, D, Turner, R   +7 more
openaire   +3 more sources

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Oral Delivery Systems for Food‐Derived Bioactive Peptides: Enhancing Stability, Bioavailability, and Health Benefits

Advanced Science, EarlyView.
Advanced delivery systems—including nanoparticles, nanoemulsions, liposomes, and hydrogels—protect food‐derived bioactive peptides from gastrointestinal degradation and bitterness. These systems enable pH‐responsive release, enhance intestinal absorption, and improve therapeutic efficacy against oxidative stress, metabolic disorders, cancer, and ...
Yu Xu, Fan Li, Runan Zhao, Tao Shu, Weihong Min, Bei‐Wei Zhu   +5 more
wiley   +1 more source