Results 181 to 190 of about 1,804,243 (315)

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes

The FEBS Journal, EarlyView.
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli, Rupesh Balaji Jayachandran, Jack Whitehead, Cédric Leyrat, Annabel v. Clanner, Guido C Paesen, Max Renner   +6 more
wiley   +1 more source

Not All Forms of Severe Malaria Impair Long-term Cognition-More Characterization, More Questions. [PDF]

Clin Infect Dis
Seydel KB, Ray STJ.
europepmc   +1 more source

Death after discharge among children living with HIV admitted with suspected sepsis in Uganda: A secondary analysis of two prospective observational studies

HIV Medicine, EarlyView.
Abstract Background Children living with HIV in low‐income countries contribute disproportionately to death after hospital discharge. This study investigates the effect of HIV on post‐discharge mortality and readmission by exploring a wide range of clinical, maternal and socioeconomic variables.
O. Mackenzie, C. Zhang, N. Kissoon, N. Ford, N. Sugandhi, E. Kumbakumba, J. Kabakyenga, C. Komugisha, N. K. Mugisha, M. O. Wiens   +9 more
wiley   +1 more source

Long-Term Cognitive Ability and Academic Achievement After Childhood Severe Malaria. [PDF]

JAMA
Bangirana P, Mellencamp KA, Ren J, Nakitende JA, Conroy AL, Datta D, Kautzman C, Goings MJ, Opoka RO, Namazzi R, Robberstad B, Idro R, John CC.   +12 more
europepmc   +1 more source

Blood Cell Counts and the Duffy Null Phenotype: Beyond Neutropenia

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT The absence of Duffy antigen expression on red blood cells, caused by a single nucleotide polymorphism in the DARC/ACKR1 gene, confers protection against malaria and is associated with lower absolute neutrophil counts (ANC) in some studied populations.
Elvira Deolinda R. P. Velloso, Andreza Oliveira dos Santos, Carla Luana Dinardo, Carolina Bonet Bub, Leandro Dinalli Santos, Mauren Fernanda Moller dos Santos, João Carlos de Campos Guerra, Denise dos Anjos Laurentis de Sousa Campos, Monica Juliana Vieira, Fábio Julio da Luz, Alfredo Mendrone‐Junior, Rosana M. Cosentino Penteado   +11 more
wiley   +1 more source

Potential Role of ACE Polymorphisms in Severe Malaria: A Case Report. [PDF]

Case Rep Infect Dis
Pisapia R, Pomicino A, Minei G, Iadevito I, Perrella A.   +4 more
europepmc   +1 more source

The Growth Costs of Malaria [PDF]

Malaria ranks among the foremost health issues facing tropical countries. In this paper, we explore the determinants of cross-country differences in malaria morbidity, and examine the linkage between malaria and economic growth.
Desmond McCarthy, Yi Wu, Holger Wolf
core  

A spatiotemporal analysis of Salmonella bacteraemia in Queensland, 2010–2019

Internal Medicine Journal, EarlyView.
Abstract Background Salmonellosis contributes to a significant burden on global healthcare systems. The impact of this foodborne bacterium is more pronounced when the infection is invasive, leading to bacteraemia and sepsis. Studies on invasive salmonellosis are few, and there is an urgent need to understand the spatial distribution of bacteraemia and ...
Naveen Manchal, Megan K Young, Maria Eugenia Castellanos, Oyelola A. Adegboye   +3 more
wiley   +1 more source

Bayesian modelling of spatio-temporal dynamics for early-warning and control of severe malaria in Cameroon. [PDF]

Parasite Epidemiol Control
Nji AM, Adegoke TM, Silal SP, Innocent A, Madeleine PF, Sylvanie MT, Tah CF, Wondeu ALD, Antinio-Nkondjio C, Bigoga JD, Leke RFG, Stresman G, Cui L, Mbacham WF.   +13 more
europepmc   +1 more source