Results 171 to 180 of about 1,804,243 (315)

The Process Is Not the Point: Moral Uncertainty and Substantive Justice in Health Care Priority Setting

Bioethics, EarlyView.
ABSTRACT Health actors must ration care due to resource constraints. But even when decision makers know the relevant empirical facts about an allocation decision—including how many patients will benefit from a service, which patients will benefit, how much each patient will benefit, and so on—these facts may not provide a clear answer about how to make
Leah Pierson
wiley   +1 more source

The Moral (Un)Desirability of New Biomedical Technologies as Potential Techno‐Fixes

Bioethics, EarlyView.
ABSTRACT The techno‐fix argument, used to argue against technological interventions that address the consequences of social problems instead of their underlying causes, is increasingly invoked in biomedical discussions. However, especially in biomedicine, the techno‐fix argument remains conceptually underdeveloped.
Lieke van Kempen, Martine C. de Vries, Nienke de Graeff   +2 more
wiley   +1 more source

Association of CD40L gene polymorphism with severe Plasmodium falciparum malaria in Indian population

Journal of Vector Borne Diseases, 2017
Background & objectives: Many host genetic factors are associated with the disease severity and fatal outcome of falciparum malaria. CD40L gene has been found to be one of the most important factors associated with malaria in African countries.
Prasanta Purohit, Pradeep Kumar Mohanty, Siris Patel, Padmalaya Das, Kishalaya Das, Jogeswar Panigrahi   +5 more
doaj  

Acting on the Voicelessness Challenge to Democratic Deliberation: A Six‐Actor Framework

Bioethics, EarlyView.
ABSTRACT Political philosophers have long recognized that key stakeholders in policy decisions—children, future generations, nonhuman animals, and individuals with severe cognitive impairments—are structurally unable to participate in the deliberative processes meant to legitimate those decisions.
Julian C. Jamison
wiley   +1 more source

Pregnancy‐Related Risk and Birth Setting Trends: Insights From Indonesian Demographic Health Survey Data

Birth, EarlyView.
New analysis from 15 years of Indonesian Demographic Health Survey Data has identified a shift from home birth to hospital birth. However, 65% of women who gave birth in hospital had no risk factors, while 13% of women who gave birth at home did report pregnancy‐related risk factors.
Kai Hodgkin, Grace Joshy, Kamalini Lokuge   +2 more
wiley   +1 more source

How Should We Treat Severe Malaria in the Setting of Artemisinin Partial Resistance? [PDF]

Am J Trop Med Hyg
Rosenthal PJ, Kamya MR, Namazzi R, John CC.   +3 more
europepmc   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

The FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath, Subhoja Chakraborty, Sampa Biswas   +2 more
wiley   +1 more source

Treating Severe Malaria

Clinical Infectious Diseases, 2020
openaire   +2 more sources

The treatment of severe falciparum malaria

BMJ, 1985
Warrell, D, White, N, Looareesuwan, S, Phillips, R, Warrell, M, Bunnag, D, Harinasuta, K   +6 more
openaire   +4 more sources

Immunomodulation Therapy to Treat Severe Malaria With Multiple Organ Failure. [PDF]

Crit Care Explor
Camara S, Buck A, Burrell M, Humes HD, Goldstein SL, Myers CN, Humes M.   +6 more
europepmc   +1 more source