Results 111 to 120 of about 755,799 (311)

A Systematic Review of Adverse Childhood Experiences and Epigenetic Age Acceleration in Later Adult Life Measured With Second and Third‐Generation Epigenetic Clocks

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT We examined the relationship between adverse childhood experiences (ACEs) and epigenetic age acceleration (EAA) in adulthood as measured by second and third generation epigenetic clocks by performing a systematic review of the literature. The electronic databases MEDLINE and EMBASE were searched on 17 July 2023.
Matthew Green   +2 more
wiley   +1 more source

Vulnerability to risky sexual behavior among patients with severe mental illness in Uganda

open access: yesDiscover Social Science and Health
Background The relationship between severe mental illness and risky sexual behaviors, defined as acts associated with a higher risk level is notably significant in sub-Saharan Africa.
C. Birungi   +4 more
doaj   +1 more source

Rüdin's Unpublished Family Study From the Early 1920s: “On the Inheritance of Manic‐Depressive Insanity”

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Ernst Rüdin, an important and controversial figure in the history of psychiatric genetics, published only one major empirical study on siblings of dementia praecox (DP) probands in 1916. He conducted a parallel study of siblings of probands with manic‐depressive insanity (MDI), but the resulting monograph, written in the early 1920s, was left ...
Kenneth S. Kendler, Astrid Klee
wiley   +1 more source

Assessment of functional disability and associated factors among people with severe mental illness attending care at public hospitals in Harar town, Eastern Ethiopia: a cross-sectional study

open access: yesBMJ Open
Objective This study aimed to assess functional disability and associated factors among people with severe mental illness attending public hospitals in Harar town, Eastern Ethiopia.Setting An institution-based cross-sectional study was conducted in ...
Betelhem Mulugeta Worku   +4 more
doaj   +1 more source

Understanding the ups and downs of living well: the voices of people experiencing early mental health recovery

open access: yesBMC Psychiatry, 2018
Background The aim of this study was to better understand early-stage mental health recovery experiences of people living with severe and persistent mental illness and complex needs.
Nicola Hancock   +4 more
doaj   +1 more source

Patient Perspectives on Psychiatric Polygenic Risk Scores in Reproductive Decision‐Making and Polygenic Embryo Screening

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Polygenic risk scores (PRS) estimate individuals' genetic risk for developing multifactorial conditions. Recent genome‐wide association studies have enabled development of psychiatric PRS, which hold potential to streamline diagnosis and treatment of psychiatric conditions.
Lauren A. Ginn   +11 more
wiley   +1 more source

Barriers and facilitators of accessing primary healthcare for patients with severe mental illness: a mixed-methods systematic review using framework synthesis

open access: yesBMC Psychiatry
Background Serious Mental Illness (SMI) is associated with significant physical health inequalities and a shortened life expectancy of approximately 20 years compared to the general population.
Elena Malogianni   +2 more
doaj   +1 more source

Stigma and public attitudes toward euthanasia or assisted suicide for psychiatric conditions: results from a general population survey in Germany

open access: yesBJPsych Open
Background With growing numbers of countries legalizing euthanasia or assisted suicide (EAS), there is a debate as to whether EAS should also be available to people with severe, treatment-resistant mental illness. Excluding mental illness as a legitimate
Georg Schomerus   +3 more
doaj   +1 more source

National Disability Insurance Scheme and Quality of Life Among Carers of Children With Autism Spectrum Disorder in Australia: A Thematic Analysis

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Diagnoses of autism spectrum disorder in Australia have increased considerably in recent years. The current study investigated how the National Disability Insurance Scheme (NDIS) impacts quality of life (QoL) among carers of children with autism spectrum disorder.
Jesse Gerhard, Sharon L. Grant
wiley   +1 more source

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