Results 121 to 130 of about 2,020,313 (253)

Profile of High Obesity Areas in: Georgia [PDF]

Obesity is a major health problem on a national level, butit is particularly persistent in certain areas. The Centers forDisease Control and Prevention\u2019s (CDC) Programs to ReduceObesity in High Obesity Areas to Boost Prevention cooperativeagreement ...

core  

Use of partial meal replacement in class 3 obesity in an Australian public weight management program

, 2020
Background: Partial meal replacement (PMR) (one or two per day) is an effective tool for short-term weight loss. Evidence and acceptability for longer term use in people with class 3 obesity (BMI>40kg/m ) are lacking.
Kormas, Nick, Deavin, Natika, Grudzinskas, Kathy, Piya, Milan K. (R19111), Chimoriya, Ritesh (R20404)   +4 more
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Dietary Patterns, Cardiometabolic Risk Factors, and the Incidence of Cardiovascular Disease in Severe Obesity

, 2015
ObjectiveThe longitudinal associations between a dietary pattern (DP) and cardiometabolic risk factors and cardiovascular disease (CVD) incidence were investigated in a cohort of adults with severe obesity.
Ambrosini, G. L., Johns, D. J., Carlsson, Lena M S,, Lindroos, Anna-Karin,, Sjöström, Lars,, Jebb, S. A.   +5 more
core   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Short-Term Changes in TNF-Alpha, IL-6 and Adiponectin Following Bariatric Surgery in Caucasian Obese Adults: An Observational Case–Control Study

Medicina
Background and Objectives: Overweight and obesity are well-known conditions that negatively impact the health and lifestyle of an individual. Bariatric surgery is one of the most efficient weight loss techniques. Besides the main effect on the bodyweight,
Razvan-Marius Ion, Adina Hutanu, Daniela Tatiana Sala, Mircea Gabriel Muresan, Stefania R. Fodor, Septimiu Voidazan, Gabriela Beresescu, Radu Mircea Neagoe   +7 more
doaj   +1 more source

Women with class 3 obesity with and without polycystic ovarian syndrome : outcomes from a multidisciplinary weight management program

, 2023
Background/Aims: Polycystic ovarian syndrome (PCOS) may affect outcomes following a weight management program (WMP). This study aimed to assess the prevalence of PCOS in women with class 3 obesity joining a multidisciplinary WMP, and compare 12-month ...
Bueno, Flavia, Grudzinskas, Kathy, Kormas, Nic, Piya, Milan K. (R19111), Gialouris, Joshua V., Chimoriya, Ritesh (R20404), Acosta Reyes, Pamela (S37563)   +6 more
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Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Obesity management in Prader–Willi syndrome: current perspectives

Diabetes, Metabolic Syndrome and Obesity, 2018
Antonino Crinò,1 Danilo Fintini,2 Sarah Bocchini,1 Graziano Grugni3 1Autoimmune Endocrine Diseases Unit, 2Endocrinology Unit, Bambino Gesù Children’s Hospital, Research Institute, Palidoro, Rome; 3Division of Auxology, Italian ...
Crinò A, Fintini D, Bocchini S, Grugni G   +3 more
doaj  

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

Left ventricular morphology and function in adolescents with severe obesity: A cardiac MRI study

, 2019
Background: Adolescents with severe obesity are at elevated risk of developing cardiovascular disease; however, the exact mechanisms are unknown. We tested the hypothesis that adolescents with severe obesity would present with adverse ventricular ...
Bolan, Patrick J., Nelson, Michael D., Ryder, Justin R., Tucker, Wesley J., Kelly, Aaron S.   +4 more
core   +2 more sources