Results 151 to 160 of about 2,097,714 (266)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

A knowledge-driven unified framework for plant disease classification and severity grading via domain adaptation. [PDF]

Plant Phenomics
Yuan Z, Wu X, Liu Y, Shuai X, Huang X, Gunarathna RDSM, Yu P, Xiao Y, Wang Q.   +8 more
europepmc   +1 more source

Severe Malaria [PDF]

Tropical Medicine & International Health, 2014
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Characterizing Alcohol Use and Expectancies for Alcohol Analgesia Among Breast Cancer Survivors With Arthralgia. [PDF]

Psychooncology
Powers JM, LaRowe LR, Somers TJ, Paice JA, Keefe FJ, Shelby RA, Yanez B, Kimmick GG, Rini C.   +8 more
europepmc   +1 more source

In Reply to Severance

Academic Medicine, 2016
Peter J, Embi, Joel, Tsevat
openaire   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Perceived stress and severity of male etomidate use disorder in China: a moderated mediation model of anxiety symptoms severity and emotion regulation difficulties. [PDF]

Front Psychol
Wang X, Le J, Tang Y, Huang Q, Qi J, Chen X, Zhao L, Zhao L, Liao Z, Shen H.   +9 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Building a Brief Multidomain Questionnaire for Gambling Dual Disorder: Psychometric Validation and RDoC-Based Dimensional Structure. [PDF]

Int J Methods Psychiatr Res
Basurte-Villamor I, Gomez-Talal I, Vega P, Azizsoltani M, Gonzalez-Peñas J, Ferre F, Szerman N.   +6 more
europepmc   +1 more source