Results 161 to 170 of about 2,097,714 (266)

Several Flaws [PDF]

Deutsches Ärzteblatt international, 2015
openaire   +2 more sources

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

"Drug Reaction with Eosinophilia and Systemic Symptoms" (DRESS): Long-term Outcomes Based on Severity - A Cohort Study. [PDF]

Acta Derm Venereol
Lipinski A, Paulmann M, Müller S, Wagner D, Mockenhaupt M.   +4 more
europepmc   +1 more source

Severe Earache [PDF]

BMJ, 1956
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Sarcopenia and Physical Function in Obstructive Sleep Apnea: A Single-Centre Cross-Sectional Study (The SOSA Study). [PDF]

Clin Respir J
Abdulsalam AJ, Ambardar R, Abdulsalam M, Khadadah S, Alkandari S, Abdulsalam A, Shehab D, Kara M, Özçakar L.   +8 more
europepmc   +1 more source

Severe hypokalaemia

International Journal of Clinical Practice, 1988
H A, Mahdy, D J, Fisher
openaire   +2 more sources

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Psychological Interventions Targeting Auditory Hallucinations in Persons With Psychotic Disorders: A Systematic Review and Meta-Analysis.

JAMA Psychiatry
Fässler L, Koop S, Opper F, Bighelli I, Leucht S, Sabé M, Bajbouj M, Knaevelsrud C, Böge K.   +8 more
europepmc   +1 more source

Association Between Inflammatory Cytokines (IL-6 and IL-10) and Trauma Severity: Correlations With Shock Index and ABC Score in Trauma Patients-A Prospective Observational Study. [PDF]

Health Sci Rep
de Oliveira RG, Shio MT, Bacchi ALL, Ribeiro AP, Sabbion RO, Colombo-Souza P.   +5 more
europepmc   +1 more source