Results 11 to 20 of about 165,945,677 (243)

Gambler's Ruin Problem in Several Dimensions

open access: yesAdvances in Applied Mathematics, 2002
Consider symmetric simple random walk on \(\{0,1, \dots,N\} \times\{0,1, \dots,M\}\) with absorbing boundaries \(x=0\), \(x=N\), \(y=0\), \(y=M\). Let \(a(i,j)\) be the expected time to absorption when starting in \((i,j)\), satisfying \[ 4a(i,j)= 4+a(i+1,j) +a(i-1,j)+ a(i,j+1)+a(i,j-1), \quad 1\leq i\leq N-1,\;1\leq j\leq M-1,\tag{*} \] with boundary ...
Andrej Kmet, Marko Petkovsek
openaire   +1 more source

ORTHOSTATIC HYPOTENSION IN PSYCHIATRY (A LITERATURE REVIEW WITH AUTHORS’ COMMENTS)

open access: yesSiberian Journal of Life Sciences and Agriculture, 2019
Purpose. To provide the reader with a thorough overview of epidemiology, potential risk factors, etiological causes, and pathogenetic mechanisms of the development of orthostatic hypotension in psychiatry.
Roman Aleksandrovich Bekker   +1 more
doaj   +1 more source

Finite-Time Ruin Probabilities for Discrete, Possibly Dependent, Claim Severities [PDF]

open access: yesMethodology and Computing in Applied Probability, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Loisel, Stéphane, Lefèvre, Claude
openaire   +3 more sources

Presenting a model to prevent and reduce employee corruption and its impact on the organization's performance [PDF]

open access: yesمدیریت و چشم انداز آموزش
The aim of the current research is to design a model for preventing and reducing administrative corruption among employees of administrative organizations and its impact on the organization's performance. In this research, in order to achieve the goal of
Hoseein Ranjbar, Mojtaba Ebrami
doaj   +1 more source

On the time value of ruin in the discrete time risk model [PDF]

open access: yes, 2002
Using an approach similar to that of Gerber and Shiu (1998), a recursive formula is given for the expected discounted penalty due at ruin, in the discrete time risk model. With it the joint distribution of three random variables is obtained; time to ruin,
Garrido, José, Li, Shuanming
core   +1 more source

A NOTE ON THE SEVERITY OF RUIN IN THE RENEWAL MODEL WITH CLAIMS OF DOMINATED VARIATION [PDF]

open access: yesBulletin of the Korean Mathematical Society, 2003
Summary: This paper investigates the tail asymptotic behavior of the severity of ruin (the deficit at ruin) in the renewal model. Under the assumption that the tail probability of the claim size is dominatedly varying a uniform asymptotic formula for the tail probability of the deficit at ruin is obtained.
openaire   +2 more sources

From ransoms to ruin: Are extortion payments by ransomware victims insurable?

open access: yesData & Policy
Cyber risk is an important consideration in today’s risk management and insurance industries. However, the statistical features of cyber risk, including concerns of solvency for cyber insurance providers, are still emerging.
Divya Ramjee, Eireann Leverett
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

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