Results 121 to 130 of about 82,704 (334)

Phosphodiesterase 4 Inhibitor Roflumilast Protects Rat Hippocampal Neurons from Sevoflurane Induced Injury via Modulation of MEK/ERK Signaling Pathway

Cellular Physiology and Biochemistry, 2018
Background/Aims: Sevoflurane, a commonly used volatile anesthetic, recently has been found has neurotoxicity in the central nervous system of neonatal rodents.
Sheng Peng, Hong-Zhu Yan, Pei-Rong Liu, Xiao-Wei Shi, Chun-Liang Liu, Qi Liu, Yu Zhang   +6 more
doaj   +1 more source

Gastrointestinal Electrical Stimulation as Prevention of Postoperative Ileus—A Blinded Randomized Controlled Porcine Trial

Neurogastroenterology &Motility, EarlyView.
In this animal study, direct postoperative electrical stimulation of the sigmoid colon shortened the length of postoperative ileus in an animal model. ABSTRACT Introduction Postoperative ileus (POI) is a condition characterized by a transient cessation of gastrointestinal function caused by surgical trauma and represents a clinical challenge after ...
Anne Kraushaar Martensen, Dennis Moegltoft Poulsen, Frederik Ehlern, Christina Brock, Jonas Amstrup Funder   +4 more
wiley   +1 more source

KATP Channel Openers Have Opposite Effects on Mitochondrial Respiration Under Different Energetic Conditions [PDF]

, 2008
Mitochondrial (m) KATP channel opening has been implicated in triggering cardiac preconditioning. Its consequence on mitochondrial respiration, however, remains unclear. We investigated the effects of two different KATP channel openers and antagonists on
Camara, Amadou K.S., Eells, Janis T., Heinen, André, Henry, Michele M., Riess, Matthias L., Stowe, David F.   +5 more
core   +2 more sources

Sevoflurane Exacerbates Cognitive Impairment Induced by Aβ1–40 in Rats through Initiating Neurotoxicity, Neuroinflammation, and Neuronal Apoptosis in Rat Hippocampus

Mediators of Inflammation, 2018
Objective This study was aimed at investigating whether sevoflurane inhalation induced cognitive impairment in rats with a possible mechanism involved in the event. Methods Thirty-two rats were randomly divided into four groups of normal saline (NS) + O2,
Yue Tian, Keyan Chen, Lidan Liu, Yunxia Dong, P. Zhao, Shan-Bin Guo   +5 more
semanticscholar   +1 more source

Consensus on the Management of Anesthetic Agents During Digestive Motility Measurements and Proposal of a Standardized Protocol for Anesthesia (French Neuro Gastroenterology Group GFNG and Committee of Anesthetic French Experts)

Neurogastroenterology &Motility, EarlyView.
Anesthesia can alter measurements during digestive endoscopies, yet no standardized protocol currently exists. Two expert groups—the French Neuro‐Gastroenterology Group (GFNG) and anesthesiologists—used the Delphi method to reach a consensus on which drugs have an influence (91 amendments), ultimately resulting in a proposed anesthesia protocol (28 ...
Domitille Renard, Thomas Clavier, Osama Abou‐Arab, Gérard Amarenco, Emmanuel Besnier, Alice Blet, Matthieu Boisson, Charlène Brochard, Benoit Coffin, Audrey De Jong, Denis Frasca, Marc Garnier, Aurelie Gouel, Jérémie Jacques, Arthur James, Yoann Launey, Anne‐Marie Leroi, Chloé Melchior, Daphné Michelet, François Mion, Maxime Nguyen, Emmanuel Rineau, Amélie Rollé, Sabine Roman, Stéphanie Sigaut, Heithem Soliman, Fabien Wuestenberghs, Frank Zerbib, Guillaume Gourcerol, Charlotte Desprez   +29 more
wiley   +1 more source

Damage-associated molecular patterns as a mechanism of sevoflurane-induced neuroinflammation in neonatal rodents [PDF]

Korean Journal of Anesthesiology
Background General anesthesia is inevitable for pediatric patients undergoing surgery, though volatile anesthetic agents may cause neuroinflammation and neurodevelopmental impairment; however, the underlying pathophysiology remains unclear.
Young-Eun Joe, Ji Hae Jun, Ju Eun Oh, Jeong-Rim Lee   +3 more
doaj   +1 more source

Sevoflurane augmentation in treatment-resistant depression: a clinical case study

Therapeutic Advances in Psychopharmacology, 2020
Compared with other inhaled anaesthetics, sevoflurane has a faster onset and offset, causes less irritation to the mucous membranes, and has a better safety profile. These characteristics warrant investigating the effect of sevoflurane in depression.
Shikai Wang, Shanfei Cheng, Min Feng, Ping Guo, Mincai Qian, Xinhua Shen, Runsen Chen, Gang Wang   +7 more
doaj   +1 more source

Sevoflurane. [PDF]

Emergency Medicine Journal, 1998
Moulton, C, Dark, P
openaire   +2 more sources

Propofol: A Medication That Changed Pediatric Anesthesia Practice

Pediatric Anesthesia, EarlyView.
ABSTRACT The introduction of propofol changed our understanding of pediatric anesthesia pharmacology, research approaches for intravenous drug study, and led to infusion pump development for the maintenance phase of anesthesia. The story of propofol development provides a blueprint for other intravenous drug development.
Brian J. Anderson, L. Ignacio Cortinez
wiley   +1 more source

Sevoflurane anesthesia alters cognitive function by activating inflammation and cell death in rats

Experimental and Therapeutic Medicine, 2018
The present study was designed to investigate the effects of sevoflurane inhalation anesthesia on the cognitive function of rats and to investigate the molecular mechanisms mediating this effect.
Rongsheng Cui, Kai Wang, Zhonglin Wang
semanticscholar   +1 more source