Results 151 to 160 of about 4,240,671 (271)

Insights into avian incomplete dosage compensation: sex-biased gene expression coevolves with neo-sex chromosome degeneration in the common whitethroat

open access: yes, 2018
<p>This upload includes sequences (1_raw_sequences.zip), sequence alignments (2_aligned_sequences.zip; 3_aligned_sequences_nogap.zip), gene divergence data (Divergence (dN, dS) data.csv; GC content.csv), and gene expression data ...
Hansson Bengt
core   +1 more source

Patients improve, patterns persist: longitudinal stability of RA joint involvement patterns

open access: yesArthritis Care &Research, Accepted Article.
Objective Rheumatoid arthritis is a heterogeneous disease. Data‐driven approaches, from synovial histology to joint involvement patterns (JIPs), have sought to define clinically meaningful subgroups. Whether these subgroups represent stable phenotypes or transient disease states remains unclear.
Tjardo Maarseveen   +24 more
wiley   +1 more source

Sex-biased migration timing in 14 Afro-Palearctic migratory birds

open access: yes, 2019
Sex-biased migration timing in 14 Afro-Palearctic migratory ...
Liechti, Felix   +23 more
core   +1 more source

Effect Modification of Cigarette Smoking on the Relationship Between Posttraumatic Stress Disorder, Other Mental Health Conditions, and Rheumatoid Arthritis Risk: A Large Case‐Control Study in US Veterans

open access: yesArthritis Care &Research, EarlyView.
Objective We examined associations of posttraumatic stress disorder (PTSD) and other mental health disorders (OMH) with rheumatoid arthritis (RA), accounting for effects of smoking. Methods We conducted a matched case‐control study, identifying incident RA cases and controls using national Veterans Health Administration data (2006–2019).
Kelsey Coziahr   +15 more
wiley   +1 more source

Integrating Genetics With Epidemiological Measurements Identifies Burden QTLs of Inflammatory Bowel Disease across 20 Countries

open access: yesAdvanced Science, EarlyView.
The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...
Chen Sun   +27 more
wiley   +1 more source

Reference genes to study the sex-biased expression of genes regulating Drosophila metabolism

open access: yesScientific Reports
AbstractSex is an important variable in biology. Notable differences have been observed between male and female Drosophila in regulation of metabolism, in response to nutritional challenges, and in phenotypes relevant for obesity and metabolic disorders.
De Groef, Sofie   +7 more
openaire   +6 more sources

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

open access: yesAdvanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao   +5 more
wiley   +1 more source

Structural and evolutionary features of red algal UV sex chromosomes

open access: yesGenome Biology
Background Sex chromosomes in red algae have remained relatively understudied, despite their fundamental role in understanding the evolution of sex determination across eukaryotes.
Agnieszka P. Lipinska   +17 more
doaj   +1 more source

Decoding Sex-Biased Gene Expression Patterns in Heart Disease [PDF]

open access: yesMayo Clinic Proceedings, 2020
Satsuki, Yamada, Andre, Terzic
openaire   +2 more sources

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

open access: yesAdvanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

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