Results 191 to 200 of about 49,304 (232)

Systematic evaluation of scallop (Argopecten irradians) SoxH reveals its crucial role in spermiogenesis with limited evidence for sex determination. [PDF]

Commun Biol
Zhang L, Wei H, Yang Y, Shu Y, Ma X, Li G, Zhang X, Cao Y, Han W, Xing Q, Wang S, Bao Z, Zhang L.   +12 more
europepmc   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

Divergent Amplification of Y-Linked Dosage-Sensitive Genes Triggers Regulatory Mismatch Underlying Cattle-Yak Male Sterility. [PDF]

Biomolecules
Wang Y, Chen Y, Zhu Z, Zeng X, Ha W, Su L, Hu L, Liu Y, Li B, Loor J, Jiang M.   +10 more
europepmc   +1 more source

RHINO: An Integrative Multi‐Omics Framework Linking Circadian Physiology to Precision Medicine

Advanced Science, EarlyView.
RHINO (RHythmic Interacting Network for multi‐Omics) is an integrative framework that maps circadian regulation across diverse genetic and disease contexts and prioritizes druggable circadian targets. Released as an AI‐powered interactive web portal, RHINO unifies genetic, regulatory, disease, and drug–target information, enabling context‐specific ...
Ying Chen, Chengxuan Chen, Dishu Zhou, Panpan Liu, Roberto E. López‐Valiente, Yuan Liu, Cam Mong La, Isabella Beraldo Xavier, Sean M. Hartig, Pradip Saha, Zheng Sun, Leng Han, Dongyin Guan   +12 more
wiley   +1 more source

Non-canonical sex chromosome evolution revealed by extreme heterogeneity in homomorphic Y chromosome differentiation in the common frog

Carpentier F, Veltsos P, Unal E, Doucette K, Fontseré R, Brelsford A, Toups M, Perrin N, Ma W.   +8 more
europepmc   +1 more source

Haplotype-resolved genomics identifies <i>cyp19a1a</i> as a candidate master sex-determining gene in golden trevally (<i>Gnathanodon speciosus</i>). [PDF]

iScience
Fan B, Guo J, Lei C, Yang S, Meng Z, Peng J, Yang Y, Shen Y, Li Y, Wang L.   +9 more
europepmc   +1 more source

Current Collector Engineering for New Efficient Bioresorbable Sodium‐Ion Batteries

Advanced Science, EarlyView.
A bioresorbable Na‐ion battery is proposed with Mo or Mg thin‐film current collectors for temporary implants. Mo‐based batteries exhibit superior electrochemical performance and stable cycling compared with Mg counterparts. XPS was used to investigate the Mo/Mg surface oxidation.
Bincy Lathakumary Vijayan, Eleonora Vandini, Vedi Kuyil Azhagan Muniraj, Hussien Hammoud, Oussama Jamai, Eve Djenizian, Marc Ramuz, Daniela Giuliani, Manuela Zavatti, Yann Tison, Hervé Martinez, Lucas Teolis, Esma Ismailova, David Moreau, Sébastien Maria, Thierry Djenizian   +15 more
wiley   +1 more source

A haplotype-resolved genome assembly of seed hemp (<i>Cannabis sativa</i>) and analysis of Y chromosome divergence from the X. [PDF]

Hortic Res
Wei H, Yang Z, Zhuang L, Pan X, Jia H, Jiang S, Li Q, Xu J, Tao A, Fang P, Qi J, Ming R, Zhang L.   +12 more
europepmc   +1 more source

Mapping Steroidogenic Perturbations Under Endocrine Disruptor Mixtures Across Demographic Subgroups: Structural and Metabolomic Insights

Advanced Science, EarlyView.
Population‐scale EDC–hormone association mapping among 4255 participants across demographic subgroups identifies phthalate metabolites as the most consistent signals associated with lower testosterone‐related markers in males. Integrative mechanistic validation prioritizes MCPP as a key phthalate metabolite linked to CYP17A1‐centered disruption of ...
Yanling Chen, Lei Huang, Yingtong Jiang, Guohong Zhao, Mengyuan Zhu, Xiulian Lu, Lang Lang, Akinpelumi Oluwatobiloba Esther, Longhao Fan, Yuqi Jiang, Chang Sun, Xiaoling Zhang, Kun Zhou, Xiaoming Ji, Minjian Chen   +14 more
wiley   +1 more source

An ancient Erysipelothrix rhusiopathiae genome recovered from 1400-year-old human remains in the Northern Caucasus. [PDF]

Sci Rep
Kritsky AA, Berezina NY, Ivanova AO, Sutormin DA, Botsmanov EI, Perevozchikova AA, Kadieva AA, Tsedilina TR, Kolesnik MV, Pavlova AV, Demidenko SV, Klimuk EI, Buzhilova AP, Severinov KV.   +13 more
europepmc   +1 more source