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Sex-determining region Y-box 2 and GA-binding proteins regulate the transcription of liver receptor homolog-1 in early embryonic cellsopenaire
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The sex-determining region of the human Y chromosome encodes a finger protein
Cell, 1987The presence or absence of the Y chromosome determines whether a mammalian embryo develops as a male or female. In humans, genetic deletion analysis of "sex-reversed" individuals has identified a small portion of the Y chromosome necessary and sufficient to induce testicular differentiation of the bipotential gonad.
David C Page, , Elizabeth M Simpson
exaly +3 more sources
Cell, 1989
The ZFY gene, located in the sex-determining region of the human Y chromosome, appears to encode a zinc-finger protein. Two homologous genes, Zfy-1 and Zfy-2, are found in the sex-determining region of the mouse Y chromosome. One or both genes may serve as the primary sex-determining signal in mice.
David C Page
exaly +3 more sources
The ZFY gene, located in the sex-determining region of the human Y chromosome, appears to encode a zinc-finger protein. Two homologous genes, Zfy-1 and Zfy-2, are found in the sex-determining region of the mouse Y chromosome. One or both genes may serve as the primary sex-determining signal in mice.
David C Page
exaly +3 more sources
Egyptian Journal of Pathology, 2022
Background Malignant mesothelioma can be difficult to be distinguished from lung adenocarcinoma without immunohistochemistry. However, conventional mesothelial markers until now do not have optimal sensitivity and specificity, necessitating the identification of new markers.
Marwa S. Abd Allah +2 more
openaire +1 more source
Background Malignant mesothelioma can be difficult to be distinguished from lung adenocarcinoma without immunohistochemistry. However, conventional mesothelial markers until now do not have optimal sensitivity and specificity, necessitating the identification of new markers.
Marwa S. Abd Allah +2 more
openaire +1 more source
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2014
Pluripotent stem cells maintain their pluripotency and undifferentiated status through a network of transcription factors. Liver receptor homolog-1 (Lrh-1) is one of these, and regulates the expression of other important transcription factors such as Oct-3/4 and Nanog.
Masafumi Kanno +9 more
openaire +2 more sources
Pluripotent stem cells maintain their pluripotency and undifferentiated status through a network of transcription factors. Liver receptor homolog-1 (Lrh-1) is one of these, and regulates the expression of other important transcription factors such as Oct-3/4 and Nanog.
Masafumi Kanno +9 more
openaire +2 more sources