Results 201 to 210 of about 49,304 (232)

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

Advanced Science, EarlyView.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten, Karen Beets, Tessa Schalley, Janne Verreycken, Gayel Duran, Daphne Lintsen, Lisa Schuetz, Xue Zhong, Rinke Nieuwschepen, Melissa Schepers, Brecht Moonen, Jeroen Bogie, Jana Van Broeckhoven, Carlo Heirman, Jurgen Van den Heuvel, Bart Vanderborght, Ismael Varela, Roxanne Nouille, Lotte Jacobs, Jessica Filtjens, Sabah Kasmi, Elise Seynaeve, Veronica Mavrovouna, Jana De Vrieze, Michael A. Brehm, Sandra Maréchal, Sophie Janssens, Florence Lambolez, Niels Hellings, Stefaan De Koker, Bieke Broux   +30 more
wiley   +1 more source

Identification of gene variants in 30 patients from southeastern China with severe hypospadias by whole-exome sequencing. [PDF]

Asian J Androl
Huang WH, Tan QQ, Zeng W, Wang HG, Cui X, Wang EH, Zhou Y, Ni WH, Zhou CM.   +8 more
europepmc   +1 more source

An Immediate‐Response Detection System for γ‐Hydroxybutyrate to Enhance Personal Safety in Social Environments

Advanced Science, EarlyView.
A graphene‐based electrical biosensor enables rapid and highly sensitive detection of GHB at 100 fm in both standard solutions and artificial urine, providing reliable point‐of‐need screening for drug‐facilitated sexual assault. The platform demonstrates strong selectivity, fast response, and a wide dynamic range, supporting accurate detection in ...
Jai Eun An, Jisung Kwak, Kyung Ho Kim, Chaeeun Kim, Sung Eun Seo, Nathaniel S. Hwang, Yong‐Sang Ryu, Hyun Seok Song, Oh Seok Kwon   +8 more
wiley   +1 more source

The role and mechanism of estrogen/estrogen receptor α in sexual identity determination of chicken somatic cells. [PDF]

Poult Sci
Jin Z, Lin X, Wu X, Wen K, Li S, Omara A, Ge J, Gong H, Zhao M, Zhang J, Gong D, Liu L, Geng T.   +12 more
europepmc   +1 more source

Sperm Sexing in Selected Animals and Humans: Methods, Applications, and Future Prospects. [PDF]

Andrology
Kinga D, Piotr J.
europepmc   +1 more source

Structural and evolutionary features of red algal UV sex chromosomes. [PDF]

Genome Biol
Lipinska AP, Cossard G, Epperlein P, Woertwein T, Molinier C, Godfroy O, Carli S, Ayres-Ostrock L, Lavaut E, Marchi F, Mauger S, Destombe C, Oliveira MC, Plastino EM, Krueger-Hadfield SA, Guillemin ML, Valero M, Coelho SM.   +17 more
europepmc   +1 more source

SRY mediates male-specific susceptibility to acute liver injury. [PDF]

Cell Commun Signal
Ke MY, Fang Y, Wei SS, Li N, Dai LZ, Zhang XG, Wu RQ, Lyu Y, Zhang XF, Dong J.   +9 more
europepmc   +1 more source

Sex-aware genome-wide assessment of de novo variants in autism across coding and noncoding regions. [PDF]

Hum Genomics
Turner TN.
europepmc   +1 more source

Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs. [PDF]

Nat Struct Mol Biol
Mota-Gómez I, Rodríguez JA, Dupont S, Hurtado A, Cadenas V, Zuber L, Maceda I, Lao O, Jedamzick J, Kühn R, Lacadie S, García-Moreno SA, Torres M, Real FM, Acemel RD, Capel B, Marti-Renom MA, Lupiáñez DG.   +17 more
europepmc   +1 more source