Results 41 to 50 of about 4,675,098 (246)

Dosage sensitivity of X-linked genes in human embryonic single cells

BMC Genomics, 2019
Background During the evolution of mammalian sex chromosomes, the degeneration of Y-linked homologs has led to a dosage imbalance between X-linked and autosomal genes.
Jian-Rong Yang, Xiaoshu Chen
doaj   +1 more source

Sex chromosome evolution in parasitic nematodes of humans

Nature Communications, 2020
Many nematode worms, including Caenorhabditis elegans have XX/XO sex determination, while other species have XY. The authors use a new genome assembly of the filarial parasite Brugia malayi and published data to show that nematode sex chromosome ...
Jeremy M. Foster, Alexandra Grote, John Mattick, Alan Tracey, Yu-Chih Tsai, Matthew Chung, James A. Cotton, Tyson A. Clark, Adam Geber, Nancy Holroyd, Jonas Korlach, Yichao Li, Silvia Libro, Sara Lustigman, Michelle L. Michalski, Michael Paulini, Matthew B. Rogers, Laura Teigen, Alan Twaddle, Lonnie Welch, Matthew Berriman, Julie C. Dunning Hotopp, Elodie Ghedin   +22 more
doaj   +1 more source

Sex chromosomal dimorphisms narrated by X-chromosome translocation in a spiny frog (Quasipaa boulengeri)

Frontiers in Zoology, 2018
Background In the general model of sex chromosome evolution for diploid dioecious organisms, the Y (or W) chromosome is derived, while the homogametic sex presumably represents the ancestral condition.
Xiuyun Yuan, Yun Xia, Xiaomao Zeng
doaj   +1 more source

Evolution of the Degenerated Y-Chromosome of the Swamp Guppy, Micropoecilia picta

Cells, 2022
The conspicuous colour sexual dimorphism of guppies has made them paradigmatic study objects for sex-linked traits and sex chromosome evolution.
Indrajit Nanda, Susanne Schories, Ivan Simeonov, Mateus Contar Adolfi, Kang Du, Claus Steinlein, Manfred Alsheimer, Thomas Haaf, Manfred Schartl   +8 more
doaj   +1 more source

The inexorable spread of a newly arisen neo-Y chromosome [PDF]

, 2008
This work was financially supported by a Natural Environment Research Council grant to RAN. (NER-B-S-2003-00859) and a studentship from Queen Mary University of London to PV.A newly arisen Y-chromosome can become established in one part of a species ...
Keller, Irene, Irene Keller, Keller Irene, Veltsos, Paris, Nichols Richard A., Veltsos, P, Nichols, Richard A., Veltsos Paris, Richard A. Nichols, Nichols, R A, Richard A Nichols, Keller, I, Nichols, RA, Paris Veltsos, Veltsos, Paris (author), P Veltsos, Keller, Irene (author), Nichols, Richard A. (author)   +17 more
core   +2 more sources

Evolutionary and developmental dynamics of sex-biased gene expression in common frogs with proto-Y chromosomes

Genome Biology, 2018
Background The patterns of gene expression on highly differentiated sex chromosomes differ drastically from those on autosomes, due to sex-specific patterns of selection and inheritance.
Wen-Juan Ma, Paris Veltsos, Roberto Sermier, Darren J Parker, Nicolas Perrin   +4 more
doaj   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

A multispecies approach for comparing sequence evolution of X-linked and autosomal sites in Drosophila [PDF]

, 2008
Population genetics models show that, under certain conditions, the X chromosome is expected to be under more efficient selection than the autosomes.
Vicoso, Beatriz, Haddrill, Penelope R, Charlesworth, Brian   +2 more
core   +4 more sources

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Turnover of sex chromosomes in the Lake Tanganyika cichlid tribe Tropheini (Teleostei: Cichlidae)

Scientific Reports
Sex chromosome replacement is frequent in many vertebrate clades, including fish, frogs, and lizards. In order to understand the mechanisms responsible for sex chromosome turnover and the early stages of sex chromosome divergence, it is necessary to ...
Kristen A. Behrens, Holger Zimmermann, Radim Blažek, Martin Reichard, Stephan Koblmüller, Thomas D. Kocher   +5 more
doaj   +1 more source