Results 111 to 120 of about 2,299,084 (348)

Shared and species-specific patterns of nascent Y chromosome evolution in two guppy species [PDF]

open access: yes, 2018
Sex chromosomes form once recombination is halted around the sex-determining locus between a homologous pair of chromosomes, resulting in a male-limited Y chromosome.
Bloch, N.I.   +4 more
core   +3 more sources

Loss of Fibronectin Fiber Tension in Glioblastoma is Associated with Microvascular Proliferations and Immune Cell Infiltration

open access: yesAdvanced Science, EarlyView.
Researchers discovered that fibronectin fibers lose their tension in specific areas of glioblastoma brain tumors, accumulating in the lumen of proliferating blood vessels and in parenchyma next to infiltrating immune cell clusters. A novel molecular tension probe enables the mapping of fibronectin's fiber tension in glioblastoma for the first time ...
Michele Crestani   +6 more
wiley   +1 more source

Massive gene amplification on a recently formed Drosophila Y chromosome. [PDF]

open access: yes, 2019
Widespread loss of genes on the Y is considered a hallmark of sex chromosome differentiation. Here we show that the initial stages of Y evolution are driven by massive amplification of distinct classes of genes. The neo-Y chromosome of Drosophila miranda
Bachtrog, Doris   +2 more
core   +1 more source

Modeling Control of Invasive Fire Ants by Gene Drive

open access: yesAdvanced Science, EarlyView.
The fire ant Solenopsis invicta is characterized by exceptional invasive capabilities, rendering conventional control ineffective. Here, we explore the use of homing suppression gene drive in fire ants by developing a spatially explicit model. Overall, these results show that target population suppression requires an extended time scale, but that gene ...
Yiran Liu   +3 more
wiley   +1 more source

Dynamics of a sex-linked deleterious mutation in populations subject to sex reversal.

open access: yesPLoS ONE, 2011
The heterogametic sex chromosomes (i.e. mammalian Y and avian W) do not usually recombine with the homogametic sex chromosomes which is known to lead into rapid degeneration of Y and W due to accumulation of deleterious mutations. On the other hand, some
Markku Karhunen
doaj   +1 more source

Influence of the X-chromosome on neuroanatomy: evidence from Turner and Klinefelter syndromes. [PDF]

open access: yes, 2014
Studies of sex effects on neurodevelopment have traditionally focused on animal models investigating hormonal influences on brain anatomy. However, more recent evidence suggests that sex chromosomes may also have direct upstream effects that act ...
Hoeft, Fumiko   +6 more
core   +2 more sources

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

open access: yesAdvanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang   +12 more
wiley   +1 more source

A specific insertion of a solo-LTR characterizes the Y-chromosome of Bryonia dioica (Cucurbitaceae)

open access: yesBMC Research Notes, 2010
Background Relatively few species of flowering plants are dioecious and even fewer are known to have sex chromosomes. Current theory posits that homomorphic sex chromosomes, such as found in Bryonia dioica (Cucurbitaceae), offer insight into the early ...
Renner Susanne S   +2 more
doaj   +1 more source

The Evolution of Sex Chromosomes and Dosage Compensation in Plants

open access: yesGenome Biology and Evolution, 2017
Plant sex chromosomes can be vastly different from those of the few historical animal model organisms from which most of our understanding of sex chromosome evolution is derived.
A. Muyle, Rylan Shearn, G. Marais
semanticscholar   +1 more source

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