Orthopteran Neo-Sex Chromosomes Reveal Dynamics of Recombination Suppression and Evolution of Supergenes. [PDF]
Jayaprasad S +16 more
europepmc +1 more source
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) often presents with cervical lymph node metastasis, with 1%–4% of cases presenting as cancer of unknown primary (CUP). CUP poses diagnostic and therapeutic challenges and is linked to poorer survival outcomes.
Robin W. Jansen +7 more
wiley +1 more source
Hierarchical architecture of neo-sex chromosomes and accelerated adaptive evolution in tortricid moths. [PDF]
Yang F +6 more
europepmc +1 more source
An Achiasmatic Mechanism That Ensures the Regular Segregation of Sex Chromosomes in Male Meiosis in the Black Spongilla-fly <i>Sisyra nigra</i> (Retzius 1738), Sisyridae, Differs from the Mechanism Commonly Observed Within Neuroptera. [PDF]
Nokkala S, Nokkala C.
europepmc +1 more source
Reproductive hormones and sex chromosomes drive sex differences in the sleep-wake cycle. [PDF]
Ralston M, Ehlen JC, Paul K.
europepmc +1 more source
Sexy ways: approaches to studying plant sex chromosomes. [PDF]
Hobza R +12 more
europepmc +1 more source
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto +21 more
wiley +1 more source
Variation in adult sex ratios in tetrapods is linked to sex chromosomes through mortality differences between males and females. [PDF]
Pipoly I +5 more
europepmc +1 more source
What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin +9 more
wiley +1 more source
Integrating polygenic and methylation risk scores for pleural mesothelioma risk stratification
What's New? Asbestos exposure is a major risk factor for pleural mesothelioma (PM). Most asbestos‐exposed individuals do not develop PM, suggesting that it arises from a complex interplay between environmental and genetic factors. This study examined the utility of polygenic risk scores (PRS) and methylation risk scores (MRS) in incorporating genetic ...
Khadija Sana Hafeez +26 more
wiley +1 more source

