Results 101 to 110 of about 8,045,025 (304)

Sex determination using image processing reveals elliptical features of the female pelvic inlet

open access: yesScientific Reports
The pelvic inlet is one of the critical constraints within the relatively narrow birth canal for the passage of the fetal head. This study tested the hypothesis that the shape of the pelvic inlet differs between females and males, with the expectation that the female pelvic inlet is more elliptical than its male counterpart.
Yasin Etli   +5 more
openaire   +3 more sources

Sex determination study in the sand fly Phlebotomus perniciosus by de novo transcriptome assembly and sex-specific profiling.

open access: yes, 2015
Trascriptome profiling of adult sexed individuals of the Leishmania vector Phlebotomus ...
PETRELLA, VALERIA   +7 more
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Thelytoky and sex determination in the Hymenoptera: mutual constraints

open access: yes, 2014
The Hymenoptera show a high propensity for transitions from arrhenotokous reproduction (diploid females develop from fertilized eggs, haploid males from unfertilized eggs) to thelytokous reproduction (diploid females develop from unfertilized eggs ...
Vorburger, C. (author)
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Climbing up the conserved sex determination cascade in tephritidae and mosquitoes.

open access: yes, 2011
Sex determination cascade studies in tephritidae and ...
SALVEMINI, MARCO   +5 more
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Genes involved in sex determination and the influence of temperature during the sexual differentiation process in fish: A review

open access: yesAfrican Journal of Biotechnology, 2013
This review attempts to group the recent hypotheses involved in the complex system of determination and sex differentiation in fish. Based on recent literature, we relate the key genes involved in the genomic cascade as the Cyp19, Dmrt1, Sox9, Foxl2, Esr, Dax1, Sf1 and Amh1 , and still little known action of temperature on them.
Helena Maria Moreira Vernetti Cristina   +8 more
openaire   +2 more sources

Role of the Y chromosome in the Ceratitis capitata sex determination and reproduction.

open access: yes, 2012
Sex determination in early embryos of ...
SALVEMINI, MARCO   +10 more
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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