Results 71 to 80 of about 3,446,536 (312)

Overall and sex-specific risk factors for subjective cognitive decline: findings from the 2015–2018 Behavioral Risk Factor Surveillance System Survey

Biology of Sex Differences, 2022
Highlights Subjective Cognitive Decline (SCD) is one of the earliest noticeable symptoms of Alzheimer’s disease and related dementias. While there is no current cure for dementia, research indicates that at least 35% of dementia risk may be modifiable by
Karen C. Schliep, William A. Barbeau, Kristine E. Lynch, Michelle K. Sorweid, Michael W. Varner, Norman L. Foster, Fares Qeadan   +6 more
doaj   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Associations of street-view greenspace exposure with cardiovascular health (Life’s Essential 8) among women in midlife

Biology of Sex Differences
Plain English summary Many women experience suboptimal cardiovascular health during midlife, increasing their risk of heart disease. Research suggests that exposure to greenspace, such as vegetation and trees, may benefit heart health, but most studies ...
Sheryl L. Rifas-Shiman, Li Yi, Izzuddin M. Aris, Pi-I Debby Lin, Marie-France Hivert, Jorge E. Chavarro, Esra Suel, Peter James, Emily Oken   +8 more
doaj   +1 more source

Sex-based differences in remote monitoring of biometric, psychometric and biomarker indices in stable ischemic heart disease

Biology of Sex Differences, 2022
Highlights Among patients with stable ischemic heart disease, adherence to remote psychometric data collection was higher among males than females There was a statistically significant ...
Lili Barsky, William Speier, Garth Fuller, Susan Cheng, Andy Kim, Sandy Joung, Corey Arnold, Shivani Dhawan, Mayra Lopez, Mitra Mastali, Irene van den Broek, Janet Wei, Brennan Spiegel, Jennifer E. Van Eyk, C. Noel Bairey Merz, Chrisandra Shufelt   +15 more
doaj   +1 more source

RETRACTED: Sex-Based Differences in Plasma Autoantibodies to Central Nervous System Proteins in Gulf War Veterans versus Healthy and Symptomatic Controls [PDF]

, 2021
Mohamed B. Abou‐Donia, Maxine Krengel, Elizabeth S. Lapadula, Clara G. Zundel, Jessica LeClair, Joseph M. Massaro, Emily Quinn, Lisa Conboy, Efi Kokkotou, Daniel Nguyen, Maria Abreu, Nancy G. Klimas, Kimberly Sullivan   +12 more
openalex   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Statistical methods for testing X chromosome variant associations: application to sex-specific characteristics of bipolar disorder

Biology of Sex Differences, 2019
Background Bipolar disorder (BD) affects both sexes, but important sex differences exist with respect to its symptoms and comorbidities. For example, rapid cycling (RC) is more prevalent in females, and alcohol use disorder (AUD) is more prevalent in ...
William A. Jons, Colin L. Colby, Susan L. McElroy, Mark A. Frye, Joanna M. Biernacka, Stacey J. Winham   +5 more
doaj   +1 more source

Untargeted metabolomics reveals sex-specific differences in lipid metabolism of adult rats exposed to dexamethasone in utero [PDF]

, 2021
Alyssa Murray, Sujeenthar Tharmalingam, Phong Nguyen, T.C. Tai   +3 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Thyroid hormone: sex-dependent role in nervous system regulation and disease

Biology of Sex Differences, 2021
Thyroid hormone (TH) regulates many functions including metabolism, cell differentiation, and nervous system development. Alteration of thyroid hormone level in the body can lead to nervous system-related problems linked to cognition, visual attention ...
Shounak Baksi, Ajay Pradhan
doaj   +1 more source