Results 11 to 20 of about 371,220 (313)

Androgens by immunoassay and mass spectrometry in children with 46,XY disorder of sex development

Endocrine Connections, 2020
Objective: Steroid measurement is a challenge in pediatric endocrinology. Currently, liquid chromatography with tandem mass spectrometry (LC-MS/MS) is considered a gold standard for this purpose. The aim of this study was to co mpare both LC-MS/MS and
Letícia Ribeiro Oliveira, Carlos Alberto Longui, Guilherme Guaragna-Filho, José Luiz Costa, Rafael Lanaro, David Antônio Silva, Maria Izabel Chiamolera, Maricilda Palandi de Mello, André Moreno Morcillo, Andrea Trevas Maciel-Guerra, Gil Guerra-Junior   +10 more
doaj   +1 more source

Nucleoporin107 mediates female sexual differentiation via Dsx

eLife, 2022
We recently identified a missense mutation in Nucleoporin107 (Nup107; D447N) underlying XX-ovarian-dysgenesis, a rare disorder characterized by underdeveloped and dysfunctional ovaries.
Tikva Shore, Tgst Levi, Rachel Kalifa, Amatzia Dreifuss, Dina Rekler, Ariella Weinberg-Shukron, Yuval Nevo, Tzofia Bialistoky, Victoria Moyal, Merav Yaffa Gold, Shira Leebhoff, David Zangen, Girish Deshpande, Offer Gerlitz   +13 more
doaj   +1 more source

Effects of the Thyroid Endocrine System on Gonadal Sex Ratios and Sex-Related Gene Expression in the Pufferfish Takifugu rubripes

Frontiers in Endocrinology, 2021
To examine the effect and mechanism of thyroid hormone on gonadal sex differentiation, Takifugu rubripes larvae were treated with goitrogen (methimazole, MET, 1000 μg/g), and thyroxine (T4, 2nM) from 25 to 80 days after hatching (dah).
Zhen Yuan, Zhen Yuan, Xufang Shen, Xufang Shen, Hongwei Yan, Hongwei Yan, Jieming Jiang, Jieming Jiang, Binwei Liu, Binwei Liu, Lei Zhang, Lei Zhang, Yumeng Wu, Yumeng Wu, Ying Liu, Ying Liu, Qi Liu, Qi Liu   +17 more
doaj   +1 more source

Putative Role of CFSH in the Eyestalk-AG-Testicular Endocrine Axis of the Swimming Crab Portunus trituberculatus

Animals, 2023
It has been shown in recent studies that the crustacean female sex hormone (CFSH) plays a crucial role in the development of secondary sexual characteristics in Decapoda crustaceans. However, research on the function of CFSH in the eyestalk-AG-testicular
Mengen Wang, Rui Xu, Shisheng Tu, Qiaoling Yu, Xi Xie, Dongfa Zhu   +5 more
doaj   +1 more source

Sexing of Embryos at the Time of Twin Reduction: A Clinical Approach

Animals, 2023
This study provides new unique information on bovine twin pairs during the late embryonic period (28–34 days of pregnancy) in relation to (1) a predictive ultrasound measurement that was differential for sexing heterosexual twins; (2) intrauterine ...
Fernando López-Gatius, Irina Garcia-Ispierto   +1 more
doaj   +1 more source

Sex determination in mythology and history [PDF]

, 2005
The history of ideas on how the sexes became divided spans at least three thousand years. The biblical account of the origin of Eve, and the opinions of the philosophers of classical Greece, have unexpected bearings on present-day ideas.
Mittwoch,Ursula, Mittwoch, U
core   +1 more source

ATRX and sex differentiation

Trends in Endocrinology & Metabolism, 2004
Most interest in the gene encoding the alpha-thalassemia, mental retardation, X-linked protein (ATRX) has traditionally been focused on its role in brain development and globin regulation. However, mutations in the ATRX gene also cause varying degrees of gonadal and urogenital abnormalities. These range from small testes to ambiguous external genitalia
Tang, Paisu, Park, Daniel J, Graves, Jennifer, Harding, Ruth E   +3 more
openaire   +3 more sources

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits [PDF]

, 2002
We tested the hypothesis that genes encoded on the sex chromosomes play a direct role in sexual differentiation of brain and behavior. We used mice in which the testis-determining gene (Sry) was moved from the Y chromosome to an autosome (by deletion of ...
Robin Lovell-Badge, De Vries, Geert, Auger, CJ, Lovell-Badge, R, Catherine J. Auger, Elka M. Scordalakes, Swain, A, Simerly, Richard B., Lovell-Badge, Robin, Richard B. Simerly, Amanda Swain, Arnold, Arthur P., Simerly, RB, Burgoyne, PS, Scordalakes, Elka M., Emilie F. Rissman, Geert J. De Vries, Liang-Yo Yang, Burgoyne, Paul S., Yang, Liang-Yo, Yang, L-Y, Rissman, EF, Rissman, Emilie F., Paul S. Burgoyne, De Vries, G, Arnold, AP, Arthur P. Arnold, Scordalakes, EM, Swain, Amanda, Auger, Catherine J.   +29 more
core   +2 more sources

FGF9 and WNT4 act as antagonistic signals to regulate mammalian sex determination [PDF]

, 2006
The genes encoding members of the wingless-related MMTV integration site (WNT) and fibroblast growth factor (FGF) families coordinate growth, morphogenesis, and differentiation in many fields of cells during development.
Robin Lovell-Badge, Sekido, R, Behringer, Richard R, Capel, Blanche, Lovell-Badge, R, DiNapoli, Leo, Blanche Capel, Chaboissier, Marie-Christine, Behringer Richard R, Lovell-Badge, Robin, DiNapoli Leo, Poulat Francis, Behringer, RR, Kim Yuna, Kobayashi, Akio, Poulat, F, Behringer, Richard,, Behringer, Richard, R., Brennan, J, Chaboissier, M-C, Capel, B, Leo DiNapoli, Ryohei Sekido, Kim, Y, Kim, Yuna, Yuna Kim, Marie-Christine Chaboissier, Francis Poulat, Jennifer Brennan, Lovell-Badge Robin, Akio Kobayashi, Kobayashi Akio, DiNapoli, L, Brennan Jennifer, Capel Blanche, Kobayashi, A, Brennan, Jennifer, Richard R Behringer, Poulat, Francis, Chaboissier Marie-Christine, Sekido, Ryohei, Sekido Ryohei   +41 more
core   +1 more source

Integrative Metabolome and Transcriptome Analysis of Flavonoid Biosynthesis Genes in Broussonetia papyrifera Leaves From the Perspective of Sex Differentiation

Frontiers in Plant Science, 2022
Flavonoids are important secondary metabolites involved in plant development and environmental responses. Sex differences in flavonoids are common in plants. Broussonetia papyrifera is a dioecious plant that is rich in flavonoids.
Peng Jiao, Li Chaoyang, Zhai Wenhan, Dai Jingyi, Zhao Yunlin, Xu Zhenggang, Xu Zhenggang   +6 more
doaj   +1 more source