Results 21 to 30 of about 357,007 (264)

408 Cases of Genital Ambiguity Followed by Single Multidisciplinary Team during 23 Years: Etiologic Diagnosis and Sex of Rearing

International Journal of Endocrinology, 2016
Objective. To evaluate diagnosis, age of referral, karyotype, and sex of rearing of cases with disorders of sex development (DSD) with ambiguous genitalia. Methods. Retrospective study during 23 years at outpatient clinic of a referral center.
Georgette Beatriz De Paula, Beatriz Amstalden Barros, Stela Carpini, Bruna Jordan Tincani, Tais Nitsch Mazzola, Mara Sanches Guaragna, Cristiane Santos da Cruz Piveta, Laurione Candido de Oliveira, Juliana Gabriel Ribeiro Andrade, Guilherme Guaragna-Filho, Pedro Perez Barbieri, Nathalia Montibeler Ferreira, Marcio Lopes Miranda, Ezequiel Moreira Gonçalves, Andre Moreno Morcillo, Nilma Lucia Viguetti-Campos, Sofia Helena Valente Lemos-Marini, Roberto Benedito de Paiva Silva, Antonia Paula Marques-de-Faria, Maricilda Palandi De Mello, Andrea Trevas Maciel-Guerra, Gil Guerra-Junior   +21 more
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Integrative Metabolome and Transcriptome Analysis of Flavonoid Biosynthesis Genes in Broussonetia papyrifera Leaves From the Perspective of Sex Differentiation

Frontiers in Plant Science, 2022
Flavonoids are important secondary metabolites involved in plant development and environmental responses. Sex differences in flavonoids are common in plants. Broussonetia papyrifera is a dioecious plant that is rich in flavonoids.
Peng Jiao, Li Chaoyang, Zhai Wenhan, Dai Jingyi, Zhao Yunlin, Xu Zhenggang, Xu Zhenggang   +6 more
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Clinical and Laboratorial Features That May Differentiate 46,XY DSD due to Partial Androgen Insensitivity and 5α-Reductase Type 2 Deficiency

International Journal of Endocrinology, 2012
The aim of this study was to search for clinical and laboratorial data in 46,XY patients with ambiguous genitalia (AG) and normal testosterone (T) synthesis that could help to distinguish partial androgen insensitivity syndrome (PAIS) from 5α-reductase ...
Nélio Neves Veiga-Junior, Pedro Augusto Rodrigues Medaets, Reginaldo José Petroli, Flávia Leme Calais, Maricilda Palandi de Mello, Carla Cristina Telles de Sousa Castro, Guilherme Guaragna-Filho, Letícia Espósito Sewaybricker, Antonia Paula Marques-de-Faria, Andréa Trevas Maciel-Guerra, Gil Guerra-Junior   +10 more
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FOXL2 and DMRT1L Are Yin and Yang Genes for Determining Timing of Sex Differentiation in the Bivalve Mollusk Patinopecten yessoensis

Frontiers in Physiology, 2018
Sex determination and differentiation have long been a research hotspot in metazoans. However, little is known about when and how sex differentiation occurs in most mollusks. In this study, we conducted a combined morphological and molecular study on sex
Ruojiao Li, Ruojiao Li, Lingling Zhang, Lingling Zhang, Wanru Li, Yang Zhang, Yangping Li, Meiwei Zhang, Liang Zhao, Xiaoli Hu, Xiaoli Hu, Shi Wang, Shi Wang, Zhenmin Bao, Zhenmin Bao   +14 more
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Histological and transcriptomic effects of 17α-methyltestosterone on zebrafish gonad development

BMC Genomics, 2017
Background Sex hormones play important roles in teleost ovarian and testicular development. In zebrafish, ovarian differentiation appears to be dictated by an oocyte-derived signal via Cyp19a1a aromatase-mediated estrogen production.
Stephanie Ling Jie Lee, Julia A. Horsfield, Michael A. Black, Kim Rutherford, Amanda Fisher, Neil J. Gemmell   +5 more
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Long-Term Follow-Up of Patients with 46,XY Partial Gonadal Dysgenesis Reared as Males

International Journal of Endocrinology, 2014
Background/Aims. Studies on 46,XY partial gonadal dysgenesis (PGD) have focused on molecular, gonadal, genital, and hormone features; little is known about follow-up. Our aim was to analyze long-term outcomes of PGD. Methods.
Juliana Gabriel Ribeiro de Andrade, Antonia Paula Marques-de-Faria, Helena Campos Fabbri, Maricilda Palandi de Mello, Gil Guerra-Júnior, Andréa Trevas Maciel-Guerra   +5 more
doaj   +1 more source

UBE2I stimulates female gonadal differentiation in chicken (Gallus gallus) embryos

Journal of Integrative Agriculture, 2021
Without known analogous sex-determining factors like SRY (sex determining region Y) in mammals, the chicken (Gallus gallus) sex determination mechanism still remains unclear, which highly restricts the biological research on chicken development and ...
Kai JIN, Jing ZHOU, Qi-sheng ZUO, Jian-cheng LI, SONG Jiuzhou, Ya-ni ZHANG, Guo-bing CHANG, Guo-hong CHEN, Bi-chun LI   +8 more
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Comparative transcriptome analysis reveals differentially expressed genes and signaling pathways between male and female mature gonads of Hemibarbus maculatus

Journal of the World Aquaculture Society, 2023
Hemibarbus maculatus is a globally important species for its value in fisheries and aquaculture. There is relatively little information available about this species' sexual development genes.
Yong Zhong, Qingping Lian, Yuange Chen, Yuanliang Duan, PeiMin He, Meiqin Wu   +5 more
doaj   +1 more source

A clinical approach to diagnosis of ambiguous genitalia

Journal of Indian Association of Pediatric Surgeons, 2019
Disorders of sex development (DSD) are a sensitive and stressful condition for the family as well as the treating physician to deal with. The main issue in managing such cases is sex assignment.
Kashish Khanna, Shilpa Sharma, Devendra K Gupta   +2 more
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Can Individuals with 47,XYY Karyotypes Exist without Male Phenotype? A Narrative Literature Review and Case Report

Frontiers in Bioscience-Scholar
Background: The 47,XYY syndrome is a genetic condition found in about 1 in 1000 male children. The expected phenotype is male but could vary greatly.
Marcelo Jones Pires, Laura Coimbra Teixeira, Luise Longo Angeloni, Julia Londero Heleno, Mariana Romano, Marcio Lopes Miranda, Tarsis Paiva Vieira, Mara Sanches Guaragna, Beatriz Amstaldem Barros, Andréa Trevas Maciel-Guerra, Gil Guerra-Junior   +10 more
doaj   +1 more source